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A Case of ALK-Rearranged Adenocarcinoma with Small Cell Carcinoma-Like Transformation and Resistance to Crizotinib

DC Field Value Language
dc.contributor.author김혜련-
dc.contributor.author심효섭-
dc.contributor.author이혜정-
dc.contributor.author조병철-
dc.contributor.author차윤진-
dc.date.accessioned2017-02-24T11:39:46Z-
dc.date.available2017-02-24T11:39:46Z-
dc.date.issued2016-
dc.identifier.issn1556-0864-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146825-
dc.description.abstractHistologic changes can be involved in resistance to anticancer drugs. Transformation to small cell lung carcinoma (SCLC) following treatment with EGFR tyrosine kinase inhibitors has been reported in patients with EGFR-mutant lung adenocarcinoma. Herein, we report a case of ALK-rearranged lung adenocarcinoma with SCLC-like histology in a metastatic abdominal nodule that was resistant to crizotinib therapy.-
dc.description.statementOfResponsibilityrestriction-
dc.format.extente55~e58-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfJOURNAL OF THORACIC ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAbdominal Neoplasms/drug therapy-
dc.subject.MESHAbdominal Neoplasms/genetics*-
dc.subject.MESHAbdominal Neoplasms/secondary-
dc.subject.MESHAdenocarcinoma/drug therapy-
dc.subject.MESHAdenocarcinoma/genetics-
dc.subject.MESHAdenocarcinoma/pathology-
dc.subject.MESHAged-
dc.subject.MESHCell Transformation, Neoplastic/drug effects-
dc.subject.MESHCell Transformation, Neoplastic/genetics*-
dc.subject.MESHCell Transformation, Neoplastic/pathology-
dc.subject.MESHDrug Resistance, Neoplasm/genetics*-
dc.subject.MESHGene Rearrangement*-
dc.subject.MESHHumans-
dc.subject.MESHLung Neoplasms/drug therapy-
dc.subject.MESHLung Neoplasms/genetics-
dc.subject.MESHLung Neoplasms/pathology-
dc.subject.MESHMale-
dc.subject.MESHProtein Kinase Inhibitors/pharmacology-
dc.subject.MESHPyrazoles/pharmacology*-
dc.subject.MESHPyridines/pharmacology*-
dc.subject.MESHReceptor Protein-Tyrosine Kinases/genetics*-
dc.subject.MESHSmall Cell Lung Carcinoma/drug therapy-
dc.subject.MESHSmall Cell Lung Carcinoma/genetics*-
dc.subject.MESHSmall Cell Lung Carcinoma/pathology-
dc.titleA Case of ALK-Rearranged Adenocarcinoma with Small Cell Carcinoma-Like Transformation and Resistance to Crizotinib-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorYoon Jin Cha-
dc.contributor.googleauthorByoung Chul Cho-
dc.contributor.googleauthorHye Ryun Kim-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorHyo Sup Shim-
dc.identifier.doi10.1016/j.jtho.2015.12.097-
dc.contributor.localIdA01166-
dc.contributor.localIdA02219-
dc.contributor.localIdA03320-
dc.contributor.localIdA03822-
dc.contributor.localIdA04001-
dc.relation.journalcodeJ01909-
dc.identifier.eissn1556-1380-
dc.identifier.pmid26752677-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S1556086415002142-
dc.subject.keywordAnaplastic lymphoma kinase-
dc.subject.keywordCrizotinib-
dc.subject.keywordLung adenocarcinoma-
dc.subject.keywordResistance-
dc.subject.keywordSmall cell lung carcinoma-
dc.contributor.alternativeNameKim, Hye Ryun-
dc.contributor.alternativeNameShim, Hyo Sup-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameCho, Byoung Chul-
dc.contributor.alternativeNameCha, Yoon Jin-
dc.contributor.affiliatedAuthorKim, Hye Ryun-
dc.contributor.affiliatedAuthorShim, Hyo Sup-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.contributor.affiliatedAuthorCho, Byoung Chul-
dc.contributor.affiliatedAuthorCha, Yoon Jin-
dc.citation.volume11-
dc.citation.number5-
dc.citation.startPage55-
dc.citation.endPage58-
dc.identifier.bibliographicCitationJOURNAL OF THORACIC ONCOLOGY, Vol.11(5) : 55-58, 2016-
dc.date.modified2017-02-24-
dc.identifier.rimsid47567-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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