Cited 15 times in
Cancer theranosis using mono-disperse, mesoporous gold nanoparticles obtained via a robust, high-yield synthetic methodology
DC Field | Value | Language |
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dc.contributor.author | 서진석 | - |
dc.contributor.author | 허용민 | - |
dc.date.accessioned | 2017-02-24T03:30:57Z | - |
dc.date.available | 2017-02-24T03:30:57Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/146362 | - |
dc.description.abstract | Porous noble metal nanoparticles exhibit many attractive nanoplasmonic features, and these structures have potential applications in many fields. However, such applications have been hindered by a lack of synthetic methods with the ability to mass-produce mono-disperse nanoparticles. Current synthetic approaches to porous gold nanostructure fabrication involve galvanic replacement approaches or electrochemical deposition methods that are generally limited by stringent multi-step protocols and relatively low yields. Here, we introduce the facile synthesis of scalable, mono-disperse, mesoporous gold nanoparticles (MPGNs) using an acidic emulsification method. This method facilitates high synthetic yields (>93%) and tunable particle sizes (130–400 nm). MPGNs exhibit enhanced payloads of gadolinium (Gd), a contrast agent for magnetic resonance imaging. Additionally, they permit photo-thermal conversion under near-infrared light (NIR) irradiation due to the increased surface area to volume ratio and the unique, structure-mediated LSPR effect. Specifically, MPGNs fabricated using our method provided Gd payloads 2–4 orders of magnitude greater than previously reported theranostic nano-probes. We believe that our novel synthetic technique will not only contribute to large-scale production of homogeneous porous gold nanoparticles, but will also promote further research in porous noble metal nanostructures. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.format.extent | 13554~13561 | - |
dc.language | English | - |
dc.publisher | Royal Society of Chemistry | - |
dc.relation.isPartOf | RSC ADVANCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Cancer theranosis using mono-disperse, mesoporous gold nanoparticles obtained via a robust, high-yield synthetic methodology | - |
dc.type | Article | - |
dc.publisher.location | England | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Radiology | - |
dc.contributor.googleauthor | Taeksu Lee | - |
dc.contributor.googleauthor | Doyeon Bang | - |
dc.contributor.googleauthor | Yong Wook Chang | - |
dc.contributor.googleauthor | Yuna Choi | - |
dc.contributor.googleauthor | Kwang Yeol Park | - |
dc.contributor.googleauthor | Aram Oh | - |
dc.contributor.googleauthor | Seungmin Han | - |
dc.contributor.googleauthor | Sun Hee Kim | - |
dc.contributor.googleauthor | Kwangyeol Lee | - |
dc.contributor.googleauthor | Jin-Suck Suh | - |
dc.contributor.googleauthor | Yong-Min Huh | - |
dc.contributor.googleauthor | Seungjoo Haam | - |
dc.identifier.doi | 10.1039/C5RA24772A | - |
dc.contributor.localId | A01916 | - |
dc.contributor.localId | A04359 | - |
dc.relation.journalcode | J02626 | - |
dc.identifier.eissn | 2046-2069 | - |
dc.identifier.url | http://pubs.rsc.org/en/content/articlelanding/2016/ra/c5ra24772a# | - |
dc.contributor.alternativeName | Suh, Jin Suck | - |
dc.contributor.alternativeName | Huh, Yong Min | - |
dc.contributor.affiliatedAuthor | Suh, Jin Suck | - |
dc.contributor.affiliatedAuthor | Huh, Yong Min | - |
dc.citation.volume | 2016 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 13554 | - |
dc.citation.endPage | 13561 | - |
dc.identifier.bibliographicCitation | RSC ADVANCES, Vol.2016(6) : 13554-13561, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47871 | - |
dc.type.rims | ART | - |
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