The effects of non-thermal atmospheric pressure plasma jet on implant surface in a dog model
Authors
장민호
Issue Date
2015
Description
Dept. of Dental Science/석사
Abstract
The purpose of this study was to investigate whether osseointegration can be improved with Non-Thermal Atmospheric Pressure Plasma Jet on SA surface implant in dogs. Implants were placed in maxilla and mandible of 6 mongrel dogs. Among the 41 SA surface implants, plasma injection was conducted on 20 implants in the experimental group, the 21 remaining non-treated implants constituting the control group. In the maxilla and mandible, 3 or 4 implants were placed, respectively. The dogs were sacrificed at either 4 or 8 weeks after implant placement. Bone volume was analyzed in a cylindrical shape determined by the 3 best threads and a circumferential zone within 50㎛ of the implant surface. A 3-dimensional bone volume analysis was conducted using micro-computed tomography and statistical analysis was performed with Wilcoxon rank-sum test.
There was a statistically significant difference between the experimental and control group at 4 weeks. (p<0.05) The mean bone volume of 4 week was 57.88% (SD: 4.55) in the experimental group and 49.21% (SD: 5.75) in the control group. At 8 weeks, mean bone volume of the experimental group (63.21%) was higher than of the control group (62.15%), but with no statistically significant difference. These results show that NTAPPJ increased bone-implant integration at 4 weeks, earlier compared to the control group.