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Repolarization heterogeneity of magnetocardiography predicts long-term prognosis in patients with acute myocardial infarction
DC Field | Value | Language |
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dc.contributor.author | 방우대 | - |
dc.date.accessioned | 2017-01-26T05:40:13Z | - |
dc.date.available | 2017-01-26T05:40:13Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/145620 | - |
dc.description | Dept. of Medicine/석사 | - |
dc.description.abstract | Background: Magnetocardiography (MCG) has been proposed as a noninvasive, diagnostic tool for risk-stratifying patients with acute myocardial infarction (AMI). This study evaluated whether MCG predicts long-term prognosis in AMI.Methods and Results: In 124 AMI patients (95 males, mean age 60±11 years), including 39 with ST-elevation myocardial infarction (MI), a 64-channel MCG was performed within 2 days after AMI. During a mean follow-up period of 68±37 months, major adverse cardiac events (MACE) were evaluated. MACE occurred in 31 (25%) patients, including 20 revascularizations, 8 deaths, and 3 re-infarctions. Non-dipole patterns were observed at 40 ms before the end of the T wave (Te40) in 89 (72%) patients. Non-dipole patterns were observed at T-peak in 77% (24/31) and 54% (50/93) of patients with and without MACE, respectively (P=0.02). Maximum current, field map angles, and distance dynamics were not different between groups. In the multivariate analysis, patients with non-dipole patterns at T-peak had increased age- and sex-adjusted hazard ratios for MACE (relative risk 2.95, 95% confidence interval 1.18-7.35) and lower cumulative MACE-free survival than those with dipole patterns (P=0.02).Conclusions: Non-dipole patterns at T-peak were more frequently observed in patients with MACE and were related to poor long-term prognosis. Thus, repolarization heterogeneity measured by MCG may be a useful predictor for AMI prognosis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.publisher | Graduate School, Yonsei University | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Repolarization heterogeneity of magnetocardiography predicts long-term prognosis in patients with acute myocardial infarction | - |
dc.title.alternative | 급성 심근경색 환자에서 magnetocardiography에 나타난 이완기 불균질성의 장기적 예후 예측 | - |
dc.type | Thesis | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.localId | A01787 | - |
dc.contributor.alternativeName | Bang, Woo Dae | - |
dc.contributor.affiliatedAuthor | 방우대 | - |
dc.type.local | Thesis | - |
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