Cited 0 times in
간문맥 혈전이 동반된 진행성 간세포암에서의 동시 항암 화학-방사선요법
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 성진실 | - |
dc.contributor.author | 안상훈 | - |
dc.contributor.author | 이도연 | - |
dc.date.accessioned | 2016-05-16T11:18:17Z | - |
dc.date.available | 2016-05-16T11:18:17Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 1226-0479 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144252 | - |
dc.description.abstract | Background/Aims: Advanced hepatocellular carcinoma with portal vein thrombosis has a poor prognosis. This study was undertaken to evaluate the therapeutic effects of concurrent chemo-radiation therapy in advanced hepatocellular carcinoma with portal vein thrombosis. Methods: A total of 54 patients with advanced hepatocellular carcinoma (TNM stage IVa) were enrolled. Nineteen patients were treated with external beam radiotherapy (4,500 cGy/ 5 weeks) and intrahepatic arterial 5-FU infusion (500 mg on 1-5 day and 30-35 day, respectively) via implanted chemoport. The others were treated with intrahepatic arterial cisplatin infusion (80 mg/m2). Results: In patients treated with concurrent chemo-radiation therapy, response rates at 2nd and 6th months were 42.1% and 26.3%, respectively. In patients treated with intrahepatic arterial cisplatin therapy, response rates at 2nd and 6th months were 2.9% and 0%, respectively. The median survival time was 11.6 months in concurrent chemo-radiation therapy and 4.8 months in intrahepatic arterial cisplatin infusion therapy. Concurrent chemo-radiation therapy produced better response rates and longer survival time than those of intrahepatic arterial cisplatin infusion therapy (p<0.05). Conclusions: Concurrent chemo-radiation therapy achieved favorable results in advanced hepatocellular carcinoma with portal vein thrombosis and can be considered as a treatment option for the management of advanced hepatocellular carcinoma | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 71~79 | - |
dc.relation.isPartOf | Korean Journal of Hepatology (대한간학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Antineoplastic Agents/administration & dosage* | - |
dc.subject.MESH | Carcinoma, Hepatocellular/complications | - |
dc.subject.MESH | Carcinoma, Hepatocellular/radiotherapy | - |
dc.subject.MESH | Carcinoma, Hepatocellular/therapy* | - |
dc.subject.MESH | Cisplatin/administration & dosage | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorouracil/administration & dosage | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infusions, Intra-Arterial | - |
dc.subject.MESH | Liver Neoplasms/complications | - |
dc.subject.MESH | Liver Neoplasms/radiotherapy | - |
dc.subject.MESH | Liver Neoplasms/therapy* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Portal Vein* | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Venous Thrombosis/complications* | - |
dc.title | 간문맥 혈전이 동반된 진행성 간세포암에서의 동시 항암 화학-방사선요법 | - |
dc.title.alternative | Concurrent Chemo - Radiation Therapy for Advanced Hepatocellular Carcinoma with Portal Vein Thrombosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | 김진석 | - |
dc.contributor.googleauthor | 한광협 | - |
dc.contributor.googleauthor | 이도연 | - |
dc.contributor.googleauthor | 성진실 | - |
dc.contributor.googleauthor | 윤영훈 | - |
dc.contributor.googleauthor | 정재연 | - |
dc.contributor.googleauthor | 안상훈 | - |
dc.contributor.googleauthor | 전재윤 | - |
dc.contributor.googleauthor | 문영명 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01956 | - |
dc.contributor.localId | A02226 | - |
dc.contributor.localId | A02718 | - |
dc.relation.journalcode | J02036 | - |
dc.identifier.pmid | 12499819 | - |
dc.subject.keyword | Neoplasm/Liver/ Hepatocellular carcinoma | - |
dc.subject.keyword | Portal vein thrombosis | - |
dc.subject.keyword | Chemo-radiation therapy | - |
dc.subject.keyword | Cisplatin | - |
dc.contributor.alternativeName | Seong, Jin Sil | - |
dc.contributor.alternativeName | Ahn, Sang Hoon | - |
dc.contributor.alternativeName | Lee, Do Yun | - |
dc.contributor.affiliatedAuthor | Seong, Jin Sil | - |
dc.contributor.affiliatedAuthor | Ahn, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Do Yun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 8 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 71 | - |
dc.citation.endPage | 79 | - |
dc.identifier.bibliographicCitation | Korean Journal of Hepatology (대한간학회지), Vol.8(1) : 71-79, 2002 | - |
dc.identifier.rimsid | 56710 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.