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입술에 발생한 Palisaded Encapsulated Neuroma 1예

Other Titles
 A Case of Palisaded Encapsulated Neuroma of the Lower Lip 
 조영훈  ;  이주희  ;  방동식  ;  김유찬 
 Korean Journal of Dermatology (대한피부과학회지), Vol.40(12) : 1552-1556, 2002 
Journal Title
Korean Journal of Dermatology(대한피부과학회지)
Issue Date
Palisaded encapsulated neuroma ; Lip
Palisaded encapsulated neuroma(PEN) is a rare intaneural neuroma. It usually occurs as a solitary, asymptomatic, skin-colored papule, and commonly affects the butterfly area of the face of middle-aged adults. However, it rarely involves oral mucosa including lip and should be differentiated from mucosal neuromas which generally occur as multiple small nodules of the lips and the anterior part of the tongue. We report a case of PEN occurring on the lower lip in a 33-year-old male. Histopathologically, it appeared as a well-circumscribed, encapsulated round nodule in the dermis. The nodule was composed of well-developed fascicles of wavy spindle cells separated by a loose matrix. Nuclear palisades were ill defined. On immunohistochemical staining, most tumor cells of the nodule were positive for S-100 protein and about 30% of tumor cells were positive for neural filament, but the capsule was negative for them. Epithelial membrane antigen was focally and discontinuously reactive on the capsule of the nodule.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Bang, Dong Sik(방동식)
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