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Total Necrosis of Hepatocellular Carcinoma Due to Spontaneous Occlusion of Feeding Artery

Authors
 Sang Cheol Lee  ;  Hye Won Chung  ;  Jae Bock Chung  ;  Young Nyun Park  ;  Sang Hoon Ahn  ;  Seung Woo Park  ;  Chae Yoon Chun  ;  Young Myoung Moon  ;  Jin Kyung Kang  ;  In Suh Park 
Citation
 YONSEI MEDICAL JOURNAL, Vol.43(1) : 123-127, 2002 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2002
MeSH
Aged ; Carcinoma, Hepatocellular/pathology* ; Humans ; Liver Neoplasms/pathology* ; Male ; Necrosis ; Thrombosis/pathology*
Keywords
Hepatocellular carcinoma, spontaneous necrosis ; spontaneous necrosis
Abstract
Spontaneous total necrosis of hepatocellular carcinoma is extremely rare, with only 15 cases reported to date in the English literature, and the involved mechanism remains unresolved. This paper describes a case of spontaneous necrosis of hepatocellular carcinoma in a 70-year-old man with chronic hepatitis. The patient suffered epigastric pain on admission and computed tomography revealed a 4 cm mass with low density in the left lobe of the liver. Fine needle aspiration biopsy revealed a few scattered, naked and irregular nuclei exhibiting nuclear hyperchromasia in the dirty necrotic background, a finding highly suggestive of malignancy. The lobectomized liver revealed a 3.5 cm, well encapsulated, round, and nearly totally necrotic mass. On microscopic examination, the tumor was found to be composed of thick trabeculae of necrotic tumor cells, supporting the diagnosis of hepatocellular carcinoma.

After surgery and throughout 13 months of follow up the patient has recovered well.
Files in This Item:
T200206052.pdf Download
DOI
10.3349/ymj.2002.43.1.123
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Park, Young Nyun(박영년) ORCID logo https://orcid.org/0000-0003-0357-7967
Ahn, Sang Hoon(안상훈) ORCID logo https://orcid.org/0000-0002-3629-4624
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/143953
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