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Excerbation of Avellino corneal dystrophy after laser in situ keratomileusis.

Authors
 Wan, Xiu Hua  ;  Lee, Hyun Chae  ;  Stulting, R. Doyle  ;  Kim, Terry  ;  Jung, Seung Eun  ;  Kim, Moon Jung  ;  Kim, Eung Kweon 
Citation
 CORNEA, Vol.21(2) : 223-226, 2002 
Journal Title
 CORNEA 
ISSN
 0277-3740 
Issue Date
2002
MeSH
Adult ; Contraindications ; Corneal Dystrophies, Hereditary/etiology* ; Corneal Dystrophies, Hereditary/genetics ; Corneal Dystrophies, Hereditary/physiopathology ; Corneal Opacity/etiology* ; Corneal Opacity/genetics ; Corneal Opacity/physiopathology ; DNA Mutational Analysis ; Disease Progression ; Extracellular Matrix Proteins* ; Female ; Humans ; Keratomileusis, Laser In Situ/adverse effects* ; Myopia/surgery ; Neoplasm Proteins/genetics ; Polymerase Chain Reaction ; Transforming Growth Factor beta/genetics ; Vision Disorders/etiology ; Vision Disorders/physiopathology ; Visual Acuity
Keywords
Avellino corneal dystrophy ; Granular corneal dys ; trophy ; Laser in situ keratomileusis ; Recurrence
Abstract
Purpose. To report a case of Avellino corneal dystrophy that increased in severity 1 year after uncomplicated laser in situ keratomileusis (LASIK) for myopia. Methods. Avellino dystrophy was confirmed by polymerase chain reaction sequencing of DNA from the patient and her parents. Results. Best spectacle-corrected visual acuity decreased from 20/20 to 20/30 12 to 20 months after LASIK owing to opacities that appeared centrally in the corneal stroma and the LASIK flap and remaining posterior stroma interface. Conclusions. LASIK is contraindicated in patients with Avellino corneal dystrophy because vision may be reduced by corneal opacities that appear in the interface of the flap and remaining posterior stroma postoperatively.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003226-200203000-00021&LSLINK=80&D=ovft
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/143487
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