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Other Titles
 BONE FORMATION BY HUMAN ALVEOLAR BONE CELLS 
Authors
 최병호  ;  박진형  ;  허진영  ;  오진록 
Citation
 Journal of the Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회지), Vol.28(1) : 42-45, 2002 
Journal Title
 Journal of the Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회지) 
ISSN
 1225-1585 
Issue Date
2002
Keywords
Tissue engineering ; Cell culture ; Alveolar bone
Abstract
Cultures of primary human alveolar bone-derived cells were established from alveolar bone chips obtained from normal individuals undergoing tooth extraction. These cells were expanded in vitro until passage 3 and used for the in vivo assays. Cells were loaded into transplantation vehicles, and transplanted subcutaneously into immunodeficient mice to study the capacities of human alveolar bone-derived cells to form bone in vivo. Transplants were harvested 12 weeks after transplantation and evaluated histologically. Of 10 human alveolar bone-derived cell transplants, two formed a bone-like tissue that featured osteocytes and mineral. Eight of the ten formed no osseous tissue. These results show that cells from normal human alveolar bone are capable of forming bone-like tissue when transplanted into immunodeficient mice.
Files in This Item:
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
Yonsei Authors
Choi, Byung Ho(최병호)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/143373
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