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췌장암 환자의 근치적 절제 후 생존과 재발 양상

Other Titles
 Survival and Recurrence Pattern after Curative Resection of Pancreatic Cancer 
 황영웅  ;  장혁재  ;  이준규  ;  서정훈  ;  박영수  ;  이진헌  ;  이세준  ;  정준표  ;  송시영  ;  정재복  ;  강진경 
 Korean Journal of Gastroenterology, Vol.38(4) : 276-283, 2001 
Journal Title
Korean Journal of Gastroenterology(대한소화기학회지)
Issue Date
Pancreatic adenocarcinoma ; Curative resecton ; Survival ; Recurrence
Background/Aims: The only hope for the cure of pancreatic adenocarcinoma is curative resection. However, the rate of recurrence after curative resection is higher than 50%. The aim, of this study were to analyze survival and the factors influencing survival and to evaluate the recurrence rate and pattern after curative resection of pancreatic adenocarcinoma. Methods: The records of 250 patients who were diagnosed as pancreatic cancer were reviewed retrospectively. We classified the patients into 3 groups (curative resection, non-curative resection, and conservative treatment) and analyzed the factors influencing survival, recurrence rate, and recurrence pattern after curative resection. Results: Curative resection were performed in 31 (12.4%) of 250 cases. The patients with curative resection was significantly prolonged median survival time than those without non-curative resection or with conservative treatment. The factors influencing survival rate after curative resection were age, lymph node involvement, and disease status. Twenty-five of the 31 cases with curative resection had recurrences after 10 months. Local retroperitoneal recurrence was 69%. Liver metastasis and lymph node metastasis were occurred in 61% and 54%, respectively. Conclusions: The survival time of the patients with pancreatic adenocarcinoma was prolonged in the cases of curative resection compared with the cases of non-curative resection or conservative treatment. However, most cases after curative resection showed recurrence. Thus, early diagnosis and early treatment should be needed to prolong the survival time of the patients with pancreatic adenocarcinoma.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Jin Kyung(강진경)
Park, Young Soo(박영수)
Suh, Jeong Hoon(서정훈)
Song, Si Young(송시영) ORCID logo https://orcid.org/0000-0002-1417-4314
Lee, Se Joon(이세준) ORCID logo https://orcid.org/0000-0002-2695-2670
Lee, Joon Kue(이준규)
Lee, Jin Hyon(이진헌)
Chang, Hyuk-Jae(장혁재) ORCID logo https://orcid.org/0000-0002-6139-7545
Chung, Jae Bock(정재복)
Chung, Jun Pyo(정준표)
Whang, Young Woong(황영웅)
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