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고흥지방 유자재배 종사자의 귤응애(Panonychus citri)알레르기

Other Titles
 Panonychus citri induced allergy among Yuzu farm workers in Koheung area 
 이재현  ;  박중원  ;  김철우  ;  박윤수  ;  고시환  ;  홍천수 
 Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기), Vol.21(3) : 525-534, 2001 
Journal Title
 Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기) 
Issue Date
Panonychus citri ; Dermatophagoides pteronyssinus ; cross allergenicity ; allergen
Background: Citrus red mite (CRM; Panonychus citri), which damages the peels and leaves of Citrus, has been reported as an important occupational allergen in Citrus farm workers. Yuzu belongs to the Citrus genus and its peels are the favorite material for tea in Korea. Aims: We evaluated the prevalence of the sensitization to CRM in Yuzu farm workers in Koheung area (Southern provinces of Korean peninsula) and analyzed the allergenicity of CRM and the cross-reactivity between CRM and Dermatophagoides pteronyssinus (DP) with the sera of the workers and urbanites. Methods: One hundred and eleven Yuzu farm workers and 36 respiratory allergic urban patients were enrolled in this study. Skin prick test (SPT) to CRM and DP was performed. CRM specific IgE was detected by ELISA and immunoblotting method. Cross-reactivity was investigated through inhibition ELISA and inhibition immunoblotting. Results: About 39% of the workers showed positive response to CRM in SPT. Revalence of allergic disease was 66%. Symptoms were associated with their work in 53% of patients. CRM-specific IgE from workers was not inhibited by DP crude antigen but CRM-specific IgE from urban patients was inhibited by DP crude antigen by an average of 70%. With immuno- blotting, we could identify 14.5, 15, 17, 18, 21, 22, 32, 33, 49.5 kDa CRM allergens with the sera of the worker. Conclusions: These results suggest that CRM is one of the unique occupational allergens to the Yuzu farm workers. Cross-reactivity between CRM and DP was found in urban patients
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Appears in Collections:
1. College of Medicine (의과대학) > Medical Research Center (임상의학연구센터) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ko, Si Hwan(고시환)
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Lee, Jae Hyun(이재현) ORCID logo https://orcid.org/0000-0002-0760-0071
Hong, Chein Soo(홍천수)
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