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후두전적출술을 받은 환자에서 레이저도플러혈류측정기를 이용한 코점막 혈류량의 변화

Other Titles
 The Change of Nasal Blood Flow after a Total Laryngectomy Determined by Laser Doppler Blood Flowmetry 
 문형진 ; 김창훈 ; 윤주헌 ; 최은창 ; 이정권 ; 한수진 
 Korean Journal of Otorhinolaryngology-Head and Neck Surgery (대한이비인후과학회지 두경부외과학), Vol.44(9) : 925~929, 2001 
Journal Title
 Korean Journal of Otorhinolaryngology-Head and Neck Surgery (대한이비인후과학회지 두경부외과학) 
Issue Date
Background and Objectives : The effects of airflow cessation on the human nasal mucosa can be conveniently studied in laryngectomees and the blood flow to nasal mucosa is an important factor in maintaining normal nasal function. Therefore, we investigated the changes in nasal mucosa blood flow after a total laryngectomy with laser Doppler flowmetry. Materials and Method : Twenty-four laryngectomees were studied and compared with 35 normal volunteers. Among 24 total laryngectomees, 9 were esophageal speakers. The laser Doppler flowmetry was performed using a Periflux 4001 (Perimed, Jrtlla, Sweden) and Perfusion unit (PU), Velocity unit (VU), and Concentration Unit (CU) were measured. The laser Doppler flowmetry data in the laryngectomees were compared with those of the normal subjects, and between the esophageal and non-esophageal speakers. Results : The difference between laryngectomees and normal subjects was statistically significant with the exception of the CU (p<0.05). Furthermore, no correlations were found between blood flow and age, and between blood flow and postoperative duration. The difference between esophageal speakers and non-esophageal speakers was statistically significant with the exception of the level of concentration (p<0.05). Conclusion : The nasal blood flow decreased after a total laryngectomy. When airflow improved, an increases in the level of blood flow was recorded. And the change of the nasal blood flow most likely occured within the first year after a total laryngectomy.
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1. 연구논문 > 1. College of Medicine > Dept. of Otorhinolaryngology
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