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Interstitial Pneumonia in Progressive Systemic Sclerosis: Serial High-Resolution CT Findings with Functional Correlation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김응엽 | - |
dc.date.accessioned | 2016-02-19T11:03:46Z | - |
dc.date.available | 2016-02-19T11:03:46Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 0363-8715 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/142311 | - |
dc.description.abstract | PURPOSE: The aim of our study was to assess the serial high-resolution CT findings and their correlation with the results of pulmonary function tests in patients with progressive systemic sclerosis (PSS) and interstitial pneumonia. METHOD: The study included 40 patients with symptoms or signs of PSS and interstitial pneumonia, who underwent serial high-resolution CT scans (mean follow-up period 39 months). Seventeen patients simultaneously had serial pulmonary function tests (mean follow-up period 40 months). On high-resolution CT, the pattern and extent of parenchymal abnormalities were retrospectively analyzed. Serial changes on high-resolution CT were correlated with the changes of pulmonary function tests. RESULTS: On initial CT, areas of ground-glass opacity (mean +/- SD extent 17.7 +/- 12.3% in all patients), irregular linear opacity (4.4 +/- 4.4% in 36 patients), small nodules (3.9 +/- 12.5% in 28), consolidation (1.9 +/- 4.2% in 13), and honeycombing (1.9 +/- 3.8% in 12) were seen. The total disease extent (p = 0.042) and extents of ground-glass opacity (18.9 +/- 15.5%; p = 0.04) and honeycombing (5.0 +/- 7.2%; p = 0.002) increased significantly on follow-up CT. Both forced vital capacity (from 2.4 +/- 0.4 to 2.0 +/- 0.4 L; p = 0.002) and forced expiratory volume in 1 s (from 2.0 +/- 0.4 to 1.6 +/- 0.3 L; p = 0.013) decreased significantly on follow-up examination. The increase in the extent of honeycombing on CT correlated significantly with the decrease in diffusing capacity for carbon monoxide (r = -0.411, p = 0.049). CONCLUSION: In patients with PSS and interstitial pneumonia, the overall extent of disease and extents of honeycombing and ground-glass opacity increase significantly on follow-up CT. Increase of honeycombing correlates well with decrease of diffusing capacity for carbon monoxide. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 757~763 | - |
dc.relation.isPartOf | JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lung Diseases, Interstitial/diagnostic imaging | - |
dc.subject.MESH | Lung Diseases, Interstitial/pathology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Respiratory Function Tests | - |
dc.subject.MESH | Scleroderma, Systemic/complications* | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | Interstitial Pneumonia in Progressive Systemic Sclerosis: Serial High-Resolution CT Findings with Functional Correlation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Eun A. Kim | - |
dc.contributor.googleauthor | Takeshi Johkoh | - |
dc.contributor.googleauthor | Kyung Soo Lee | - |
dc.contributor.googleauthor | Kazuya Ichikado | - |
dc.contributor.googleauthor | Eun-Mi Koh | - |
dc.contributor.googleauthor | Tae Sung Kim | - |
dc.contributor.googleauthor | Eung Yeop Kim | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00832 | - |
dc.relation.journalcode | J01350 | - |
dc.identifier.eissn | 1532-3145 | - |
dc.identifier.pmid | 11584237 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-200109000-00015&LSLINK=80&D=ovft | - |
dc.contributor.alternativeName | Kim, Eung Yeop | - |
dc.contributor.affiliatedAuthor | Kim, Eung Yeop | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 25 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 757 | - |
dc.citation.endPage | 763 | - |
dc.identifier.bibliographicCitation | JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.25(5) : 757-763, 2001 | - |
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