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Interstitial Pneumonia in Progressive Systemic Sclerosis: Serial High-Resolution CT Findings with Functional Correlation

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dc.contributor.author김응엽-
dc.date.accessioned2016-02-19T11:03:46Z-
dc.date.available2016-02-19T11:03:46Z-
dc.date.issued2001-
dc.identifier.issn0363-8715-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/142311-
dc.description.abstractPURPOSE: The aim of our study was to assess the serial high-resolution CT findings and their correlation with the results of pulmonary function tests in patients with progressive systemic sclerosis (PSS) and interstitial pneumonia. METHOD: The study included 40 patients with symptoms or signs of PSS and interstitial pneumonia, who underwent serial high-resolution CT scans (mean follow-up period 39 months). Seventeen patients simultaneously had serial pulmonary function tests (mean follow-up period 40 months). On high-resolution CT, the pattern and extent of parenchymal abnormalities were retrospectively analyzed. Serial changes on high-resolution CT were correlated with the changes of pulmonary function tests. RESULTS: On initial CT, areas of ground-glass opacity (mean +/- SD extent 17.7 +/- 12.3% in all patients), irregular linear opacity (4.4 +/- 4.4% in 36 patients), small nodules (3.9 +/- 12.5% in 28), consolidation (1.9 +/- 4.2% in 13), and honeycombing (1.9 +/- 3.8% in 12) were seen. The total disease extent (p = 0.042) and extents of ground-glass opacity (18.9 +/- 15.5%; p = 0.04) and honeycombing (5.0 +/- 7.2%; p = 0.002) increased significantly on follow-up CT. Both forced vital capacity (from 2.4 +/- 0.4 to 2.0 +/- 0.4 L; p = 0.002) and forced expiratory volume in 1 s (from 2.0 +/- 0.4 to 1.6 +/- 0.3 L; p = 0.013) decreased significantly on follow-up examination. The increase in the extent of honeycombing on CT correlated significantly with the decrease in diffusing capacity for carbon monoxide (r = -0.411, p = 0.049). CONCLUSION: In patients with PSS and interstitial pneumonia, the overall extent of disease and extents of honeycombing and ground-glass opacity increase significantly on follow-up CT. Increase of honeycombing correlates well with decrease of diffusing capacity for carbon monoxide.-
dc.description.statementOfResponsibilityopen-
dc.format.extent757~763-
dc.relation.isPartOfJOURNAL OF COMPUTER ASSISTED TOMOGRAPHY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHDisease Progression-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHLung Diseases, Interstitial/diagnostic imaging-
dc.subject.MESHLung Diseases, Interstitial/pathology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRespiratory Function Tests-
dc.subject.MESHScleroderma, Systemic/complications*-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHTomography, X-Ray Computed-
dc.titleInterstitial Pneumonia in Progressive Systemic Sclerosis: Serial High-Resolution CT Findings with Functional Correlation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorEun A. Kim-
dc.contributor.googleauthorTakeshi Johkoh-
dc.contributor.googleauthorKyung Soo Lee-
dc.contributor.googleauthorKazuya Ichikado-
dc.contributor.googleauthorEun-Mi Koh-
dc.contributor.googleauthorTae Sung Kim-
dc.contributor.googleauthorEung Yeop Kim-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00832-
dc.relation.journalcodeJ01350-
dc.identifier.eissn1532-3145-
dc.identifier.pmid11584237-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-200109000-00015&LSLINK=80&D=ovft-
dc.contributor.alternativeNameKim, Eung Yeop-
dc.contributor.affiliatedAuthorKim, Eung Yeop-
dc.rights.accessRightsnot free-
dc.citation.volume25-
dc.citation.number5-
dc.citation.startPage757-
dc.citation.endPage763-
dc.identifier.bibliographicCitationJOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.25(5) : 757-763, 2001-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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