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An observational study of surface versus endovascular cooling techniques in cardiac arrest patients: a propensity-matched analysis

DC FieldValueLanguage
dc.contributor.author박유석-
dc.date.accessioned2016-02-04T12:03:06Z-
dc.date.available2016-02-04T12:03:06Z-
dc.date.issued2015-
dc.identifier.issn1364-8535-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141781-
dc.description.abstractINTRODUCTION: Various methods and devices have been described for cooling after cardiac arrest, but the ideal cooling method remains unclear. The aim of this study was to compare the neurological outcomes, efficacies and adverse events of surface and endovascular cooling techniques in cardiac arrest patients. METHODS: We performed a multicenter, retrospective, registry-based study of adult cardiac arrest patients treated with therapeutic hypothermia presenting to 24 hospitals across South Korea from 2007 to 2012. We included patients who received therapeutic hypothermia using overall surface or endovascular cooling devices and compared the neurological outcomes, efficacies and adverse events of both cooling techniques. To adjust for differences in the baseline characteristics of each cooling method, we performed one-to-one matching by the propensity score. RESULTS: In total, 803 patients were included in the analysis. Of these patients, 559 underwent surface cooling, and the remaining 244 patients underwent endovascular cooling. In the unmatched cohort, a greater number of adverse events occurred in the surface cooling group. Surface cooling was significantly associated with a poor neurological outcome (cerebral performance category 3-5) at hospital discharge (p = 0.01). After propensity score matching, surface cooling was not associated with poor neurological outcome and hospital mortality [odds ratio (OR): 1.26, 95% confidence interval (CI): 0.81-1.96, p = 0.31 and OR: 0.85, 95% CI: 0.55-1.30, p = 0.44, respectively]. Although surface cooling was associated with an increased incidence of adverse events (such as overcooling, rebound hyperthermia, rewarming related hypoglycemia and hypotension) compared with endovascular cooling, these complications were not associated with surface cooling using hydrogel pads. CONCLUSIONS: In the overall matched cohort, no significant difference in neurological outcomes and hospital morality was observed between the surface and endovascular cooling methods.-
dc.description.statementOfResponsibilityopen-
dc.format.extent85-
dc.relation.isPartOfCRITICAL CARE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCardiopulmonary Resuscitation/methods*-
dc.subject.MESHFemale-
dc.subject.MESHHeart Arrest/mortality-
dc.subject.MESHHeart Arrest/therapy*-
dc.subject.MESHHospital Mortality-
dc.subject.MESHHumans-
dc.subject.MESHHypothermia, Induced/adverse effects-
dc.subject.MESHHypothermia, Induced/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPropensity Score-
dc.subject.MESHRegistries-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRewarming/adverse effects-
dc.subject.MESHTreatment Outcome-
dc.titleAn observational study of surface versus endovascular cooling techniques in cardiac arrest patients: a propensity-matched analysis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Emergency Medicine (응급의학)-
dc.contributor.googleauthorSang Hoon Oh-
dc.contributor.googleauthorJoo Suk Oh-
dc.contributor.googleauthorYoung-Min Kim-
dc.contributor.googleauthorKyu Nam Park-
dc.contributor.googleauthorSeung Pill Choi-
dc.contributor.googleauthorGi Woon Kim-
dc.contributor.googleauthorKyung Woon Jeung-
dc.contributor.googleauthorTae Chang Jang-
dc.contributor.googleauthorYoo Seok Park-
dc.contributor.googleauthorYeon Young Kyong-
dc.identifier.doi10.1186/s13054-015-0819-7-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01592-
dc.relation.journalcodeJ00652-
dc.identifier.eissn1466-609X-
dc.identifier.pmid25880667-
dc.subject.keywordPropensity Score-
dc.subject.keywordPropensity Score Match-
dc.subject.keywordTherapeutic Hypothermia-
dc.subject.keywordSurface Cool-
dc.subject.keywordCerebral Performance Category-
dc.contributor.alternativeNamePark, Yoo Seok-
dc.contributor.affiliatedAuthorPark, Yoo Seok-
dc.rights.accessRightsfree-
dc.citation.volume19-
dc.citation.startPage85-
dc.identifier.bibliographicCitationCRITICAL CARE, Vol.19 : 85, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers

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