Cited 22 times in
Pathological Evaluation of Radiation-Induced Vascular Lesions of the Brain: Distinct from De Novo Cavernous Hemangioma
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 차윤진 | - |
dc.contributor.author | 고지은 | - |
dc.contributor.author | 김세훈 | - |
dc.contributor.author | 신현주 | - |
dc.contributor.author | 장종희 | - |
dc.contributor.author | 조남훈 | - |
dc.contributor.author | 남지해 | - |
dc.date.accessioned | 2016-02-04T12:01:30Z | - |
dc.date.available | 2016-02-04T12:01:30Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/141724 | - |
dc.description.abstract | PURPOSE: We aimed to evaluate the histologic and radiologic findings of vascular lesions after stereotactic radiosurgery (SRS) categorized as radiation-induced cavernous hemangioma (RICH). MATERIALS AND METHODS: Among 89 patients who underwent neurosurgery for cavernous hemangioma, eight RICHs from 7 patients and 10 de novo CHs from 10 patients were selected for histopathological and radiological comparison. RESULTS: Histologically, RICHs showed hematoma-like gross appearance. Microscopically, RICH exhibited a hematoma-like area accompanied by proliferation of thin-walled vasculature with fibrin deposits and infiltrating foamy macrophages. In contrast, CHs demonstrated localized malformed vasculature containing fresh and old clotted blood on gross examination. Typically, CHs consisted of thick, ectatic hyalinized vessels lined by endothelium under a light microscope. Magnetic resonance imaging of RICHs revealed some overlapping but distinct features with CHs, including enhancing cystic and solid components with absence or incomplete popcorn-like appearance and partial hemosiderin rims. CONCLUSION: Together with histologic and radiologic findings, RICH may result from blood-filled space after tissue destruction by SRS, accompanied with radiation-induced reactive changes rather than vascular malformation. Thus, the term "RICH" would be inappropriate, because it is more likely to be an inactive organizing hematoma rather than proliferation of malformed vasculature. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Brain/pathology* | - |
dc.subject.MESH | Brain Neoplasms/pathology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hemangioma, Cavernous/complications | - |
dc.subject.MESH | Hemangioma, Cavernous/pathology* | - |
dc.subject.MESH | Hemangioma, Cavernous/surgery | - |
dc.subject.MESH | Hematoma/surgery | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Radiosurgery/adverse effects | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Pathological Evaluation of Radiation-Induced Vascular Lesions of the Brain: Distinct from De Novo Cavernous Hemangioma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Yoon Jin Cha | - |
dc.contributor.googleauthor | Ji Hae Nahm | - |
dc.contributor.googleauthor | Ji Eun Ko | - |
dc.contributor.googleauthor | Hyun Joo Shin | - |
dc.contributor.googleauthor | Jong-Hee Chang | - |
dc.contributor.googleauthor | Nam Hoon Cho | - |
dc.contributor.googleauthor | Se Hoon Kim | - |
dc.identifier.doi | 10.3349/ymj.2015.56.6.1714 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04001 | - |
dc.contributor.localId | A00147 | - |
dc.contributor.localId | A00610 | - |
dc.contributor.localId | A02178 | - |
dc.contributor.localId | A03470 | - |
dc.contributor.localId | A03812 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 26446658 | - |
dc.subject.keyword | Brain | - |
dc.subject.keyword | cavernous | - |
dc.subject.keyword | central nervous system | - |
dc.subject.keyword | hemangioma | - |
dc.subject.keyword | radiosurgery | - |
dc.contributor.alternativeName | Cha, Yoon Jin | - |
dc.contributor.alternativeName | Koh, Ji Eun | - |
dc.contributor.alternativeName | Kim, Se Hoon | - |
dc.contributor.alternativeName | Shin, Hyun Joo | - |
dc.contributor.alternativeName | Chang, Jong Hee | - |
dc.contributor.alternativeName | Cho, Nam Hoon | - |
dc.contributor.affiliatedAuthor | Cha, Yoon Jin | - |
dc.contributor.affiliatedAuthor | Koh, Ji Eun | - |
dc.contributor.affiliatedAuthor | Kim, Se Hoon | - |
dc.contributor.affiliatedAuthor | Shin, Hyun Joo | - |
dc.contributor.affiliatedAuthor | Chang, Jong Hee | - |
dc.contributor.affiliatedAuthor | Cho, Nam Hoon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 56 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1714 | - |
dc.citation.endPage | 1720 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.56(6) : 1714-1720, 2015 | - |
dc.identifier.rimsid | 30844 | - |
dc.type.rims | ART | - |
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