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Outcomes of Hemodialysis in Children: A 35-Year Experience at Severance Hospital

 Hyun-Seung Shin  ;  Ji Young Oh  ;  Se Jin Park  ;  Ji Hong Kim  ;  Jae Seung Lee  ;  Jae Il Shin 
 Yonsei Medical Journal, Vol.56(4) : 1007-1014, 2015 
Journal Title
 Yonsei Medical Journal 
Issue Date
PURPOSE: The aim of this study was to analyze the results of children treated with hemodialysis (HD) at Severance Hospital over 35 years in terms of incidence, etiologies, characteristics, complications, and clinical outcomes. MATERIALS AND METHODS: We analyzed 46 children admitted to Severance Hospital who had undergone HD between January 1979 and December 2013. RESULTS: The main etiologies of the 23 end-stage renal disease (ESRD) patients who had received HD were chronic glomerulonephritis (7 patients, 30.4%) and congenital anomalies of the kidney and urinary tract (7 patients, 30.4%), whereas the etiology of the 23 acute kidney injury (AKI) patients was hemolytic uremic syndrome (6 patients, 26.1%). Compared with ESRD patients, hemocatheter placement in the femoral vein was preferred over the subclavian or internal jugular vein in the AKI patients (p=0.012). The most common complication was catheter related complication (10 patients, 21.7%). The site of hemocatheter insertion was not related to the frequency of oozing. Placing the hemocatheter in the femoral vein resulted in significantly more events of catheter obstruction than insertion in the internal jugular vein or the subclavian vein (p=0.001). Disequilibrium syndrome occurred more frequently in older patients (p=0.004), as well as patients with a greater body weight (p=0.008) and a higher systolic and diastolic blood pressure before HD (systolic: p=0.021; diastolic: p=0.040). CONCLUSION: Based on the 35 years of experience in our center, HD can be sufficiently and safely carried out even in children without significant complications.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실)
Yonsei Authors
김지홍(Kim, Ji Hong) ORCID logo https://orcid.org/0000-0001-5352-5423
신재일(Shin, Jae Il) ORCID logo https://orcid.org/0000-0003-2326-1820
오지영(Oh, Ji Young) ORCID logo https://orcid.org/0000-0003-3552-8465
이재승(Lee, Jae Seung)
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