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Effects of Vitreomacular Adhesion on Age-Related Macular Degeneration

Authors
 Eui Chun Kang  ;  Hyoung Jun Koh 
Citation
 Journal of Ophthalmology, Vol.2015 : 865083-865083, 2015 
Journal Title
 Journal of Ophthalmology 
ISSN
 2090-004X 
Issue Date
2015
Abstract
Herein, we review the association between vitreomacular adhesion (VMA) and neovascular age-related macular degeneration (AMD). Meta-analyses have shown that eyes with neovascular AMD are twice as likely to have VMA as normal eyes. VMA in neovascular AMD may induce inflammation, macular traction, decrease in oxygenation, sequestering of vascular endothelial growth factor (VEGF), and other cytokines or may directly stimulate VEGF production. VMA may also interfere with the treatment effects of anti-VEGF therapy, which is the standard treatment for neovascular AMD, and releasing VMA can improve the treatment response to anti-VEGF treatment in neovascular AMD. We also reviewed currently available methods of relieving VMA.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141240
DOI
10.1155/2015/865083
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실)
Yonsei Authors
강의천(Kang, Eui Chun) ; 고형준(Koh, Hyoung Jun)
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