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Prediction of Micrometastasis (< 1 cm) to Pelvic Lymph Nodes in Prostate Cancer: Role of Preoperative MRI

DC FieldValueLanguage
dc.contributor.author나군호-
dc.contributor.author박성윤-
dc.contributor.author오영택-
dc.contributor.author정대철-
dc.contributor.author조남훈-
dc.contributor.author최영득-
dc.date.accessioned2016-02-04T11:47:01Z-
dc.date.available2016-02-04T11:47:01Z-
dc.date.issued2015-
dc.identifier.issn0361-803X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/141193-
dc.description.abstractOBJECTIVE: The purpose of this study was to retrospectively investigate whether preoperative MRI plays a key role in clinical prediction of micrometastasis (< 1 cm) to pelvic lymph nodes in prostate cancer. MATERIALS AND METHODS: One hundred one patients with prostate cancer who underwent preoperative MRI and radical prostatectomy with pelvic lymph node dissection were included. None of the patients had a pelvic lymph node with a short-axis diameter of 1 cm or larger on MRI. Both clinical (prostate-specific antigen, biopsy Gleason score, greatest percentage of biopsy core, and percentage of positive cores) and MRI parameters (tumor apparent diffusion coefficient and tumor staging) were assessed. The univariate, multivariate, and ROC curve analyses were conducted. RESULTS: Of 101 patients, nine (8.9%) had pelvic lymph node metastases. In univariate analysis, all of the clinical and MRI parameters were related to micrometastasis to pelvic lymph nodes (p < 0.05). However, multivariate analysis revealed that only preoperative MRI stage was significant (p = 0.044). AUC of preoperative MRI stage was 0.954 (odds ratio, 21.7). Respective sensitivity and specificity of preoperative tumor staging by MRI were 100% and 65.2% with cutoff of T3a or more, and 88.9% and 94.6% with cutoff of T3b for predicting micrometastasis to pelvic lymph nodes. CONCLUSION: Preoperative MRI staging may play a role in prediction of micrometastasis (< 1 cm) to pelvic lymph nodes in prostate cancer.-
dc.description.statementOfResponsibilityopen-
dc.format.extentW328~W334-
dc.relation.isPartOfAmerican Journal of Roentgenology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titlePrediction of Micrometastasis (< 1 cm) to Pelvic Lymph Nodes in Prostate Cancer: Role of Preoperative MRI-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorSung Yoon Park-
dc.contributor.googleauthorYoung Taik Oh-
dc.contributor.googleauthorDae Chul Jung-
dc.contributor.googleauthorNam Hoon Cho-
dc.contributor.googleauthorYoung Deuk Choi-
dc.contributor.googleauthorKoon Ho Rha-
dc.identifier.doi10.2214/AJR.14.14138-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01227-
dc.contributor.localIdA01509-
dc.contributor.localIdA02390-
dc.contributor.localIdA03592-
dc.contributor.localIdA03812-
dc.contributor.localIdA04111-
dc.relation.journalcodeJ00116-
dc.identifier.urlhttp://www.ajronline.org/doi/abs/10.2214/AJR.14.14138-
dc.contributor.alternativeNameRha, Koon Ho-
dc.contributor.alternativeNamePark, Sung Yoon-
dc.contributor.alternativeNameOh, Young Taik-
dc.contributor.alternativeNameJung, Dae Chul-
dc.contributor.alternativeNameCho, Nam Hoon-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.affiliatedAuthorRha, Koon Ho-
dc.contributor.affiliatedAuthorPark, Sung Yoon-
dc.contributor.affiliatedAuthorOh, Young Taik-
dc.contributor.affiliatedAuthorJung, Dae Chul-
dc.contributor.affiliatedAuthorCho, Nam Hoon-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.rights.accessRightsnot free-
dc.citation.volume205-
dc.citation.number3-
dc.citation.startPage328-
dc.citation.endPage334-
dc.identifier.bibliographicCitationAmerican Journal of Roentgenology, Vol.205(3) : 328-334, 2015-
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)

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