Cited 10 times in
Relationship between Myocardial Extracellular Space Expansion Estimated with Post-Contrast T1 Mapping MRI and Left Ventricular Remodeling and Neurohormonal Activation in Patients with Dilated Cardiomyopathy
DC Field | Value | Language |
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dc.contributor.author | 정혜문 | - |
dc.contributor.author | 최병욱 | - |
dc.contributor.author | 최의영 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 홍그루 | - |
dc.contributor.author | 김영진 | - |
dc.contributor.author | 김태훈 | - |
dc.contributor.author | 박철환 | - |
dc.contributor.author | 손정우 | - |
dc.contributor.author | 윤지현 | - |
dc.contributor.author | 임세중 | - |
dc.contributor.author | 장혁재 | - |
dc.contributor.author | 정남식 | - |
dc.date.accessioned | 2016-02-04T11:45:20Z | - |
dc.date.available | 2016-02-04T11:45:20Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1229-6929 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/141128 | - |
dc.description.abstract | OBJECTIVE: Post-contrast T1 values are closely related to the degree of myocardial extracellular space expansion. We determined the relationship between post-contrast T1 values and left ventricular (LV) diastolic function, LV remodeling, and neurohormonal activation in patients with dilated cardiomyopathy (DCM). MATERIALS AND METHODS: Fifty-nine patients with DCM (mean age, 55 ± 15 years; 41 males and 18 females) who underwent both 1.5T magnetic resonance imaging and echocardiography were enrolled. The post-contrast 10-minute T1 value was generated from inversion time scout images obtained using the Look-Locker inversion recovery sequence and a curve-fitting algorithm. The T1 sample volume was obtained from three interventricular septal points, and the mean T1 value was used for analysis. The N-Terminal pro-B-type natriuretic peptide (NT-proBNP) level was measured in 40 patients. RESULTS: The mean LV ejection fraction was 24 ± 9% and the post-T1 value was 254.5 ± 46.4 ms. The post-contrast T1 value was significantly correlated with systolic longitudinal septal velocity (s'), peak late diastolic velocity of the mitral annulus (a'), the diastolic elastance index (Ed, [E/e']/stroke volume), LV mass/volume ratio, LV end-diastolic wall stress, and LV end-systolic wall stress. In a multivariate analysis without NT-proBNP, T1 values were independently correlated with Ed (β = -0.351, p = 0.016) and the LV mass/volume ratio (β = 0.495, p = 0.001). When NT-proBNP was used in the analysis, NT-proBNP was independently correlated with the T1 values (β = -0.339, p = 0.017). CONCLUSION: Post-contrast T1 is closely related to LV remodeling, diastolic function, and neurohormonal activation in patients with DCM. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1153~1162 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Algorithms | - |
dc.subject.MESH | Blood Pressure | - |
dc.subject.MESH | Cardiomyopathy, Dilated/diagnosis* | - |
dc.subject.MESH | Cardiomyopathy, Dilated/diagnostic imaging | - |
dc.subject.MESH | Echocardiography | - |
dc.subject.MESH | Extracellular Space/diagnostic imaging* | - |
dc.subject.MESH | Extracellular Space/physiology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Ventricles/diagnostic imaging | - |
dc.subject.MESH | Heart Ventricles/physiopathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Natriuretic Peptide, Brain/analysis | - |
dc.subject.MESH | Peptide Fragments/analysis | - |
dc.subject.MESH | Radiography | - |
dc.subject.MESH | Ventricular Remodeling* | - |
dc.title | Relationship between Myocardial Extracellular Space Expansion Estimated with Post-Contrast T1 Mapping MRI and Left Ventricular Remodeling and Neurohormonal Activation in Patients with Dilated Cardiomyopathy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Ji Hyun Yoon | - |
dc.contributor.googleauthor | Jung Woo Son | - |
dc.contributor.googleauthor | Hyemoon Chung | - |
dc.contributor.googleauthor | Chul Hwan Park | - |
dc.contributor.googleauthor | Young Jin Kim | - |
dc.contributor.googleauthor | Hyuk Jae Chang | - |
dc.contributor.googleauthor | Geu Ru Hong | - |
dc.contributor.googleauthor | Tae Hoon Kim | - |
dc.contributor.googleauthor | Jong Won Ha | - |
dc.contributor.googleauthor | Byoung Wook Choi | - |
dc.contributor.googleauthor | Se Joong Rim | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.contributor.googleauthor | Eui Young Choi | - |
dc.identifier.doi | 10.3348/kjr.2015.16.5.1153 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03779 | - |
dc.contributor.localId | A04059 | - |
dc.contributor.localId | A04165 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A04386 | - |
dc.contributor.localId | A01722 | - |
dc.contributor.localId | A01991 | - |
dc.contributor.localId | A02609 | - |
dc.contributor.localId | A03372 | - |
dc.contributor.localId | A03490 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A01086 | - |
dc.contributor.localId | A00727 | - |
dc.relation.journalcode | J02884 | - |
dc.identifier.eissn | 2005-8330 | - |
dc.identifier.pmid | 26355278 | - |
dc.subject.keyword | Diastolic function | - |
dc.subject.keyword | Dilated cardiomyopathy | - |
dc.subject.keyword | T1 mapping | - |
dc.contributor.alternativeName | Chung, Hye Moon | - |
dc.contributor.alternativeName | Choi, Byoung Wook | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.alternativeName | Hong, Geu Ru | - |
dc.contributor.alternativeName | Kim, Young Jin | - |
dc.contributor.alternativeName | Kim, Tae Hoon | - |
dc.contributor.alternativeName | Park, Chul Hwan | - |
dc.contributor.alternativeName | Son, Jung Woo | - |
dc.contributor.alternativeName | Yoon, Ji Hyun | - |
dc.contributor.alternativeName | Rim, Se Joong | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Chung, Hye Moon | - |
dc.contributor.affiliatedAuthor | Choi, Byoung Wook | - |
dc.contributor.affiliatedAuthor | Choi, Eui Young | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Hong, Geu Ru | - |
dc.contributor.affiliatedAuthor | Park, Chul Hwan | - |
dc.contributor.affiliatedAuthor | Son, Jung Woo | - |
dc.contributor.affiliatedAuthor | Yoon, Ji Hyun | - |
dc.contributor.affiliatedAuthor | Rim, Se Joong | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Kim, Tae Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Young Jin | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 16 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1153 | - |
dc.citation.endPage | 1162 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF RADIOLOGY, Vol.16(5) : 1153-1162, 2015 | - |
dc.identifier.rimsid | 30532 | - |
dc.type.rims | ART | - |
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