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메토트렉세이트 사용 중 발생한 간을 침범한광범위큰B세포림프종 1예

Other Titles
 A Case of Diffuse Large B-cell Lymphoma with Liver Involvement in a 67-Year-Old Woman Given Methotrexate for Rheumatoid Arthritis 
Authors
 천재영  ;  최희승  ;  조세희  ;  이서희  ;  조미옥  ;  이민영  ;  김유리 
Citation
 Korean Journal of Medicine, Vol.88(6) : 715-718, 2015 
Journal Title
 Korean Journal of Medicine 
ISSN
 1226-329X 
Issue Date
2015
Abstract
Prolonged inflammation or immunosuppression may cause lymphoproliferative disorders (LPD). Rheumatoid arthritis (RA) itself causes LPD. The immunosuppressive drug methotrexate (MTX) is used widely to treat RA, and is also related to the development of lymphoma. Although the detailed pathogenesis and association are still controversial, care is needed when managing patients with RA treated with MTX. Many reports indicate that discontinuing MTX can induce the regression of LPD. Here, we describe a case of diffuse large B-cell lymphoma that presented with liver involvement in a 67-year-old woman who had used MTX for RA for 15 years.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/140858
Files in This Item:
T201503015.pdf Download
DOI
10.3904/kjm.2015.88.6.715
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
김유리(Kim, Yu Ri) ORCID logo https://orcid.org/0000-0001-5505-0142
조세희(Jo, Se Hee)
최희승(Choi, Heeseung)
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