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Novel methods for clinical risk stratification in patients with colorectal liver metastases

DC FieldValueLanguage
dc.contributor.author김남규-
dc.contributor.author노재경-
dc.contributor.author민병소-
dc.contributor.author백승혁-
dc.contributor.author신상준-
dc.contributor.author안중배-
dc.contributor.author이강영-
dc.contributor.author임준석-
dc.contributor.author차인호-
dc.contributor.author최기홍-
dc.contributor.author최진섭-
dc.contributor.author허혁-
dc.date.accessioned2016-02-04T11:32:39Z-
dc.date.available2016-02-04T11:32:39Z-
dc.date.issued2015-
dc.identifier.issn1598-2998-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140662-
dc.description.abstractPURPOSE: Colorectal cancer patients with liver-confined metastases are classified as stage IV, but their prognoses can differ from metastases at other sites. In this study, we suggest a novel method for risk stratification using clinically effective factors. MATERIALS AND METHODS: Data on 566 consecutive patients with colorectal liver metastasis (CLM) between 1989 and 2010 were analyzed. This analysis was based on principal component analysis (PCA). RESULTS: The survival rate was affected by carcinoembryonic antigen (CEA) level (p < 0.001; risk ratio, 1.90), distribution of liver metastasis (p=0.014; risk ratio, 1.46), and disease-free interval (DFI; p < 0.001; risk ratio, 1.98). When patients were divided into three groups according to PCA score using significantly affected factors, they showed significantly different survival patterns (p < 0.001). CONCLUSION: The PCA scoring system based on CEA level, distribution of liver metastasis, and DFI may be useful for preoperatively determining prognoses in order to assist in clinical decisionmaking and designing future clinical trials for CLM treatment.-
dc.description.statementOfResponsibilityopen-
dc.format.extent242~250-
dc.relation.isPartOfCancer Research and Treatment-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleNovel methods for clinical risk stratification in patients with colorectal liver metastases-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral and Maxillofacial Surgery (구강악안면외과학)-
dc.contributor.googleauthorKi-Yeol Kim-
dc.contributor.googleauthorNam Kyu Kim-
dc.contributor.googleauthorIn-Ho Cha-
dc.contributor.googleauthorJoong Bae Ahn-
dc.contributor.googleauthorJin Sub Choi-
dc.contributor.googleauthorGi-Hong Choi-
dc.contributor.googleauthorJoon Suk Lim-
dc.contributor.googleauthorKang Young Lee-
dc.contributor.googleauthorSeung Hyuk Baik-
dc.contributor.googleauthorByung Soh Min-
dc.contributor.googleauthorHyuk Hur-
dc.contributor.googleauthorJae Kyung Roh-
dc.contributor.googleauthorSang Joon Shin-
dc.identifier.doi10.4143/crt.2014.066-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00353-
dc.contributor.localIdA01290-
dc.contributor.localIdA01402-
dc.contributor.localIdA01827-
dc.contributor.localIdA02105-
dc.contributor.localIdA02262-
dc.contributor.localIdA02640-
dc.contributor.localIdA03408-
dc.contributor.localIdA04046-
dc.contributor.localIdA04199-
dc.contributor.localIdA04373-
dc.contributor.localIdA04002-
dc.relation.journalcodeJ00453-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.alternativeNameRoh, Jae Kyung-
dc.contributor.alternativeNameMin, Byung Soh-
dc.contributor.alternativeNameBaik, Seung Hyuk-
dc.contributor.alternativeNameShin, Sang Joon-
dc.contributor.alternativeNameAhn, Joong Bae-
dc.contributor.alternativeNameLee, Kang Young-
dc.contributor.alternativeNameLim, Joon Seok-
dc.contributor.alternativeNameCha, In Ho-
dc.contributor.alternativeNameChoi, Gi Hong-
dc.contributor.alternativeNameChoi, Jin Sub-
dc.contributor.alternativeNameHur, Hyuk-
dc.contributor.affiliatedAuthorKim, Nam Kyu-
dc.contributor.affiliatedAuthorRoh, Jae Kyung-
dc.contributor.affiliatedAuthorMin, Byung Soh-
dc.contributor.affiliatedAuthorBaik, Seung Hyuk-
dc.contributor.affiliatedAuthorShin, Sang Joon-
dc.contributor.affiliatedAuthorAhn, Joong Bae-
dc.contributor.affiliatedAuthorLee, Kang Young-
dc.contributor.affiliatedAuthorLim, Joon Seok-
dc.contributor.affiliatedAuthorChoi, Gi Hong-
dc.contributor.affiliatedAuthorChoi, Jin Sub-
dc.contributor.affiliatedAuthorHur, Hyuk-
dc.contributor.affiliatedAuthorCha, In Ho-
dc.rights.accessRightsfree-
dc.citation.volume47-
dc.citation.number2-
dc.citation.startPage242-
dc.citation.endPage250-
dc.identifier.bibliographicCitationCancer Research and Treatment, Vol.47(2) : 242-250, 2015-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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