247 519

Cited 2 times in

Repeat Targeted Prostate Biopsy under Guidance of Multiparametric MRI-Correlated Real-Time Contrast-Enhanced Ultrasound for Patients with Previous Negative Biopsy and Elevated Prostate-Specific Antigen: A Prospective Study

DC Field Value Language
dc.contributor.author나군호-
dc.contributor.author오영택-
dc.contributor.author정대철-
dc.contributor.author최영득-
dc.contributor.author홍성준-
dc.date.accessioned2016-02-04T11:26:01Z-
dc.date.available2016-02-04T11:26:01Z-
dc.date.issued2015-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/140412-
dc.description.abstractOBJECTIVES: To prospectively determine whether multi-parametric MRI (mpMRI) - contrast-enhanced ultrasound (CEUS) correlated, imaging-guided target biopsy (TB) method could improve the detection of prostate cancer in re-biopsy setting of patients with prior negative biopsy. METHODS: From 2012 to 2014, a total of 42 Korean men with a negative result from previous systematic biopsy (SB) and elevated prostate-specific antigen underwent 3T mpMRI and real-time CEUS guided TB. Target lesions were determined by fusion of mpMRI and CEUS. Subsequently, 12-core SB was performed by a different radiologist. We compared core-based cancer detection rates (CaDR) using the generalized linear mixed model (GLIMMIX) for each biopsy method. RESULTS: Core-based CaDR was higher in TB (17.92%, 38 of 212 cores) than in SB (6.15%, 31 of 504 cores) (p < 0.0001; GLIMMIX). In the cancer-positive TB cores, CaDR with suspicious lesions by mpMRI was higher than that by CEUS (86.8% vs. 60.5%, p= 0.02; paired t-test) and concordant rate between mpMRI and CEUS was significantly different with discordant rate (48% vs. 52%, p=0.04; McNemar's test). CONCLUSION: The mpMRI-CEUS correlated TB technique for the repeat prostate biopsy of patients with prior negative biopsy can improve CaDR based on the number of cores taken.-
dc.description.statementOfResponsibilityopen-
dc.format.extente0130671-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHBiopsy, Large-Core Needle-
dc.subject.MESHContrast Media/metabolism*-
dc.subject.MESHEndoscopic Ultrasound-Guided Fine Needle Aspiration/methods*-
dc.subject.MESHFalse Negative Reactions-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPrognosis-
dc.subject.MESHProstate-Specific Antigen/blood*-
dc.subject.MESHProstatic Neoplasms/blood*-
dc.subject.MESHProstatic Neoplasms/metabolism-
dc.subject.MESHProstatic Neoplasms/pathology*-
dc.titleRepeat Targeted Prostate Biopsy under Guidance of Multiparametric MRI-Correlated Real-Time Contrast-Enhanced Ultrasound for Patients with Previous Negative Biopsy and Elevated Prostate-Specific Antigen: A Prospective Study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorDong Ryul Jang-
dc.contributor.googleauthorDae Chul Jung-
dc.contributor.googleauthorYoung Taik Oh-
dc.contributor.googleauthorSongmi Noh-
dc.contributor.googleauthorKyunghwa Han-
dc.contributor.googleauthorKiwook Kim-
dc.contributor.googleauthorKoon-Ho Rha-
dc.contributor.googleauthorYoung Deuk Choi-
dc.contributor.googleauthorSung Joon Hong-
dc.identifier.doi10.1371/journal.pone.0130671-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01227-
dc.contributor.localIdA02390-
dc.contributor.localIdA03592-
dc.contributor.localIdA04111-
dc.contributor.localIdA04402-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid26083348-
dc.contributor.alternativeNameRha, Koon Ho-
dc.contributor.alternativeNameOh, Young Taik-
dc.contributor.alternativeNameJung, Dae Chul-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.alternativeNameHong, Sung Joon-
dc.contributor.affiliatedAuthorRha, Koon Ho-
dc.contributor.affiliatedAuthorOh, Young Taik-
dc.contributor.affiliatedAuthorJung, Dae Chul-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.contributor.affiliatedAuthorHong, Sung Joon-
dc.rights.accessRightsfree-
dc.citation.volume10-
dc.citation.number6-
dc.citation.startPagee0130671-
dc.identifier.bibliographicCitationPLOS ONE, Vol.10(6) : e0130671, 2015-
dc.identifier.rimsid51992-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.