Cited 4 times in
Feasibility of Selective Catheter-Directed Coronary Computed Tomography Angiography Using Ultralow-Dose Intracoronary Contrast Injection in a Swine Model
DC Field | Value | Language |
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dc.contributor.author | 박세일 | - |
dc.contributor.author | 심학준 | - |
dc.contributor.author | 장혁재 | - |
dc.date.accessioned | 2016-02-04T11:25:15Z | - |
dc.date.available | 2016-02-04T11:25:15Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0020-9996 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140385 | - |
dc.description.abstract | OBJECTIVE: Selective catheter-directed intracoronary contrast injected coronary computed tomography angiography (selective CCTA) has recently been introduced for on-site evaluation of coronary artery disease during coronary artery catheterization. In this study, we aimed to develop a feasible protocol for selective CCTA using ultralow-dose contrast medium as compared with conventional intravenous CCTA (IV CCTA). MATERIALS AND METHODS: A novel combined system incorporating coronary angiography and a 320-detector row computed tomographic scanner was used to study 4 swine (35-40 kg) under animal institutional review board approval. A selective CCTA scan was simultaneously performed with an injection of 13.13 mgI/mL of modulated contrast medium at multiple different injection rates including 2, 3, and 4 mL/s and different total injection volumes of either 20 or 30 mL. Intravenous CCTA was performed with 60 mL of contrast medium, followed by 30 mL of saline chaser at 5 mL/s. Coronary mean and peak intensity, transluminal attenuation gradient, as well as 3-dimensional maximum intensity projections were obtained. RESULTS: Attenuation values (mean ± standard error, in Hounsfield units [HUs]) of selective CCTA for the left anterior descending (LAD) and right coronary artery (RCA) using the various combinations of injection rates and total injection volumes were as follows: 20 mL at 2 mL/s (LAD, 270.3 ± 20.4 HU; RCA, 322.6 ± 7.4 HU), 20 mL at 3 mL/s (LAD, 262.9 ± 20.4 HU; RCA, 264.7 ± 7.4 HU), 30 mL at 3 mL/s (LAD, 276.8 ± 20.4 HU; RCA, 274.0 ± 7.4 HU), 20 mL at 4 mL/s (LAD, 268.0 ± 20.4 HU; RCA, 277.7 ± 7.4 HU), and 30 mL at 4 mL/s (LAD, 251.3 ± 20.4 HU; RCA, 334.7 ± 7.4 HU). The representative protocol of the selective CCTA studies produced results within the optimal enhancement range (approximately 250-350 HU) for all segments, and comparison of transluminal attenuation gradient data with selective CCTA and IV CCTA studies demonstrated that the former method was more homogenous (-1.5245 and -1.7558 for LAD as well as 0.0459 and 0.0799 for RCA, respectively). Notably, the volume of iodine contrast medium used for selective CCTA was reported to be 1.09% (0.2 g) of IV CCTA (24 g). CONCLUSIONS: The current findings demonstrate the feasibility of selective CCTA using ultralow-dose intracoronary contrast injection. This technique may provide additional means of coronary evaluation in patients who may require strategic planning before a procedure using a combined modality system. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 449~455 | - |
dc.relation.isPartOf | INVESTIGATIVE RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cardiac Catheterization/methods* | - |
dc.subject.MESH | Contrast Media/administration & dosage | - |
dc.subject.MESH | Coronary Angiography/methods* | - |
dc.subject.MESH | Dose-Response Relationship, Drug | - |
dc.subject.MESH | Feasibility Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Image Enhancement/methods* | - |
dc.subject.MESH | Image Interpretation, Computer-Assisted/methods | - |
dc.subject.MESH | Iopamidol/administration & dosage | - |
dc.subject.MESH | Iopamidol/analogs & derivatives* | - |
dc.subject.MESH | Radiation Protection/methods* | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Tomography, X-Ray Computed/methods* | - |
dc.subject.MESH | Wine | - |
dc.title | Feasibility of Selective Catheter-Directed Coronary Computed Tomography Angiography Using Ultralow-Dose Intracoronary Contrast Injection in a Swine Model | - |
dc.type | Article | - |
dc.contributor.college | Researcher Institutes (부설 연구소) | - |
dc.contributor.department | Cardiovascular Product Evaluation Center (심혈관제품유효성평가센터) | - |
dc.contributor.googleauthor | Hong, Youngtaek | - |
dc.contributor.googleauthor | Shin, Sanghoon | - |
dc.contributor.googleauthor | Park, Hyung-Bok | - |
dc.contributor.googleauthor | Lee, Byoung Kwon | - |
dc.contributor.googleauthor | Arsanjani, Reza | - |
dc.contributor.googleauthor | Hartaigh, Bríain ó | - |
dc.contributor.googleauthor | Ha, Seongmin | - |
dc.contributor.googleauthor | Jang, Yeonggul | - |
dc.contributor.googleauthor | Jeon, Byunghwan | - |
dc.contributor.googleauthor | Jung, Sunghee | - |
dc.contributor.googleauthor | Park, Se-Il | - |
dc.contributor.googleauthor | Sung, Ji Min | - |
dc.contributor.googleauthor | Shim, Hackjoon | - |
dc.contributor.googleauthor | Chang, Hyuk-Jae | - |
dc.identifier.doi | 10.1097/RLI.0000000000000150 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01522 | - |
dc.contributor.localId | A02215 | - |
dc.contributor.localId | A03490 | - |
dc.relation.journalcode | J01188 | - |
dc.identifier.eissn | 1536-0210 | - |
dc.identifier.pmid | 25816215 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004424-201507000-00005&LSLINK=80&D=ovft | - |
dc.subject.keyword | computed tomography | - |
dc.subject.keyword | catheter | - |
dc.subject.keyword | coronary angiography | - |
dc.subject.keyword | contrast media | - |
dc.contributor.alternativeName | Park, Se Il | - |
dc.contributor.alternativeName | Shim, Hack Joon | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Park, Se Il | - |
dc.contributor.affiliatedAuthor | Shim, Hack Joon | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 50 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 449 | - |
dc.citation.endPage | 455 | - |
dc.identifier.bibliographicCitation | INVESTIGATIVE RADIOLOGY, Vol.50(7) : 449-455, 2015 | - |
dc.identifier.rimsid | 51974 | - |
dc.type.rims | ART | - |
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