Cited 27 times in
Adding MRI to ultrasound and ultrasound-guided fine-needle aspiration reduces the false-negative rate of axillary lymph node metastasis diagnosis in breast cancer patients
DC Field | Value | Language |
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dc.contributor.author | 김민정 | - |
dc.contributor.author | 김은경 | - |
dc.contributor.author | 문희정 | - |
dc.contributor.author | 윤정현 | - |
dc.contributor.author | 현수정 | - |
dc.date.accessioned | 2016-02-04T11:22:08Z | - |
dc.date.available | 2016-02-04T11:22:08Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0009-9260 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140270 | - |
dc.description.abstract | AIM: To evaluate whether adding magnetic resonance imaging (MRI) to ultrasound (US) and US-guided fine-needle aspiration (US-FNA) can reduce the false-negative rate (FNR) in the diagnosis of axillary lymph node metastasis (ALNM) in breast cancer patients, and to assess false-negative diagnosis of N2 and N3 disease when adding MRI to US and US-FNA. MATERIALS AND METHODS: From March 2012 to February 2013, 497 breast cancer patients were included in the study. ALNM was evaluated according to US and US-FNA prior to MRI. Second-look US was performed when MRI showed positive findings of ALNM. If second-look US also revealed a positive finding, US-FNA was performed. Diagnostic performance, including FNR, was calculated for US and US-FNA with and without MRI. The negative predictive value (NPV) of N2 and N3 disease was evaluated in negative cases based on US and US-FNA with MRI. RESULTS: A total of 159 of 497 (32.0%) patients were found to have ALNM. Among them, 92 patients were diagnosed with metastasis on US and US-FNA. When adding MRI to US and US-FNA, an additional six patients were diagnosed with metastasis. The FNR of diagnosis of ALNM was improved by the addition of MRI (42.1% versus 38.4%, p = 0.0143). The NPV for N2 and N3 disease was 98% (391/399) based on US and US-FNA with MRI. CONCLUSION: Adding MRI to US and US-FNA could reduce the FNR of the diagnosis of ALNM. Furthermore, US and US-FNA with MRI may exclude 98% of N2 and N3 disease. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 716~722 | - |
dc.relation.isPartOf | CLINICAL RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Axilla | - |
dc.subject.MESH | Biopsy, Fine-Needle/methods | - |
dc.subject.MESH | Breast Neoplasms*/diagnostic imaging | - |
dc.subject.MESH | Breast Neoplasms*/pathology | - |
dc.subject.MESH | False Negative Reactions | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymph Nodes*/diagnostic imaging | - |
dc.subject.MESH | Lymph Nodes*/pathology | - |
dc.subject.MESH | Lymphatic Metastasis*/diagnostic imaging | - |
dc.subject.MESH | Lymphatic Metastasis*/pathology | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Sentinel Lymph Node Biopsy/methods* | - |
dc.subject.MESH | Ultrasonography, Interventional/methods* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Adding MRI to ultrasound and ultrasound-guided fine-needle aspiration reduces the false-negative rate of axillary lymph node metastasis diagnosis in breast cancer patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | S.J. Hyun | - |
dc.contributor.googleauthor | E.-K. Kim | - |
dc.contributor.googleauthor | J.H. Yoon | - |
dc.contributor.googleauthor | H.J. Moon | - |
dc.contributor.googleauthor | M.J. Kim | - |
dc.identifier.doi | 10.1016/j.crad.2015.03.004 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00473 | - |
dc.contributor.localId | A00801 | - |
dc.contributor.localId | A01397 | - |
dc.contributor.localId | A02595 | - |
dc.contributor.localId | A04380 | - |
dc.relation.journalcode | J00610 | - |
dc.identifier.eissn | 1365-229X | - |
dc.identifier.pmid | 25917544 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0009926015001002 | - |
dc.contributor.alternativeName | Kim, Min Jung | - |
dc.contributor.alternativeName | Kim, Eun Kyung | - |
dc.contributor.alternativeName | Moon, Heui Jeong | - |
dc.contributor.alternativeName | Yoon, Jung Hyun | - |
dc.contributor.alternativeName | Hyun, Su Jeong | - |
dc.contributor.affiliatedAuthor | Kim, Min Jung | - |
dc.contributor.affiliatedAuthor | Kim, Eun-Kyung | - |
dc.contributor.affiliatedAuthor | Moon, Heui Jeong | - |
dc.contributor.affiliatedAuthor | Yoon, Jung Hyun | - |
dc.contributor.affiliatedAuthor | Hyun, Su Jeong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 70 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 716 | - |
dc.citation.endPage | 722 | - |
dc.identifier.bibliographicCitation | CLINICAL RADIOLOGY, Vol.70(7) : 716-722, 2015 | - |
dc.identifier.rimsid | 50392 | - |
dc.type.rims | ART | - |
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