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Further evidence of a dissociation between decision-making under ambiguity and decision-making under risk in obsessive-compulsive disorder

Authors
 Hae Won Kim  ;  Jee In Kang  ;  Kee Namkoong  ;  Kyungun Jhung  ;  Ra Yeon Ha  ;  Se Joo Kim 
Citation
 JOURNAL OF AFFECTIVE DISORDERS, Vol.176 : 118-124, 2015 
Journal Title
 JOURNAL OF AFFECTIVE DISORDERS 
ISSN
 0165-0327 
Issue Date
2015
MeSH
Adult ; Case-Control Studies ; Decision Making* ; Executive Function ; Female ; Humans ; Male ; Neuropsychological Tests ; Obsessive-Compulsive Disorder/psychology* ; Risk-Taking* ; Uncertainty* ; Young Adult
Keywords
Decision-making ; Game of dice task ; Iowa gambling task ; Obsessive–compulsive disorder
Abstract
BACKGROUND: Deficits in decision-making have been suggested as a key concept in understanding the symptoms of obsessive-compulsive disorder (OCD). However, evidence in the extant literature remains inconclusive on whether patients with OCD show inferior performance on laboratory decision-making tasks. The aims of the present study were therefore to (1) assess decision-making under ambiguity and under risk in patients with OCD and (2) study the influence of neuropsychological and clinical variables on decision-making in OCD. METHODS: The sample consisted of 65 patients with OCD and 58 controls. The Iowa gambling task (IGT) and the game of dice task (GDT) were used to examine decision-making under ambiguity and decision-making under risk, respectively. In addition, reversal learning and executive function were assessed in terms of their relationship with decision-making tasks. RESULTS: Patients with OCD showed impairment in the IGT, but not in the GDT. Reversal learning was neither impaired nor correlated with IGT performance. Among the clinical variables, illness severity and depression were associated with IGT scores. Executive function was impaired, but no significant relationship was found between executive function and GDT performance in OCD patients. LIMITATIONS: Almost all OCD patients were on medication when they performed decision-making tasks. CONCLUSIONS: Patients with OCD are impaired in decision-making under ambiguity, but not under risk. These findings demonstrate that decision-making processes are dissociated in OCD.
Full Text
http://www.sciencedirect.com/science/article/pii/S0165032715000737
DOI
10.1016/j.jad.2015.01.060
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Jee In(강지인) ORCID logo https://orcid.org/0000-0002-2818-7183
Kim, Se Joo(김세주) ORCID logo https://orcid.org/0000-0002-5438-8210
Kim, Hae Won(김혜원) ORCID logo https://orcid.org/0000-0002-9321-8361
Namkoong, Kee(남궁기) ORCID logo https://orcid.org/0000-0003-1400-8057
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/140260
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