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Evaluation of penetration effect of resin infiltrant using optical coherence tomography

 J.H. Min  ;  D. Inaba  ;  H.K. Kwon  ;  J.H. Chung  ;  B.I. Kim 
 JOURNAL OF DENTISTRY, Vol.43(6) : 720-725, 2015 
Journal Title
Issue Date
Animals ; Cattle ; Dental Caries/diagnostic imaging* ; Dental Caries/metabolism ; Dental Enamel/diagnostic imaging ; Dental Enamel/metabolism ; Dental Enamel Permeability ; Microscopy, Confocal/methods ; Refractometry ; Resin Cements/chemistry* ; Resin Cements/pharmacokinetics ; Tomography, Optical Coherence/methods*
Confocal laser scanning microscopy (CLSM) ; Early caries lesion (EC) ; Optical coherence tomography (OCT) ; Resin infiltrant (RI)
OBJECTIVE: The aims of this in vitro study were to investigate whether optical coherence tomography (OCT) could analyze infiltration of resin infiltrant (RI) into early dental caries (EC), and to confirm the correlation between the results of OCT and confocal laser scanning microscopy (CLSM) for evaluation of RI infiltration into EC.

METHODS: Sound bovine permanent teeth were used to produce sixty specimens by making two windows on the teeth. Each 20 specimens were demineralized for 20, 30, and 40 days, and the RI was treated on one of the windows. As a result, the images of the fifty-two specimens were taken by OCT and CLSM. The demineralized lesion depth (LDOCT and LDCLSM) and the infiltrated depth of RI into lesion (IDOCT and IDCLSM) obtained from the OCT and the CLSM were analyzed. The correlations between the LDOCT and the LDCLSM, and between the IDOCT and the IDCLSM, were analyzed by Pearson correlation and intra-class correlation. Also, Bland-Altman plot was constructed to assess the agreement between the IDOCT and the IDCLSM, and the IDOCT divided by refractive index of RI and the IDCLSM.

RESULTS: The Pearson correlation coefficient and intra-class correlation of 0.75 and 0.83 (95% CI: 0.71-0.91) respectively were confirmed between the LDOCT and the LDCLSM (p<0.001), and 0.59 and 0.71 (95% CI: 0.50-0.84) respectively were observed between the IDOCT and the IDCLSM (p<0.001). The lower bias was confirmed in Bland-Altman plot between adjusted IDOCT and the IDCLSM than between the IDOCT and the IDCLSM.

CONCLUSION: The OCT was the promising quantitative evaluation method for RI penetrated into EC.
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2. College of Dentistry (치과대학) > Dept. of Preventive Dentistry and Public Oral Health (예방치과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ho Keun(권호근)
Kim, Baek Il(김백일) ORCID logo https://orcid.org/0000-0001-8234-2327
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