Cited 8 times in
Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport
DC Field | Value | Language |
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dc.contributor.author | 서진석 | - |
dc.contributor.author | 허용민 | - |
dc.date.accessioned | 2016-02-04T11:19:06Z | - |
dc.date.available | 2016-02-04T11:19:06Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1998-0124 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/140157 | - |
dc.description.abstract | Vesicular pH modulates the function of many organelles and plays a pivotal role in cell metabolism processes such as proliferation and apoptosis. Here, we introduce a simple colourimetric redox-polyaniline nanoindicator, which can detect and quantify a broader biogenic pH range with superior sensitivity compared to pre-established trafficking agents employing one-dimensional turn-on of the FRET signal. We fabricated polyaniline-based nanoprobes, which exhibited convertible transition states according to the proton levels, as an in situ indicator of vesicular transport pH. Silica-coated Fe3O4–MnO heterometal nanoparticles were synthesised and utilised as a metal oxidant to polymerise the aniline monomer. Finally, silica-coated polyaniline nanoparticles with adsorbed fluorophores Cy3 and Cy7 (FPSNICy3 and FPSNICy7) were fabricated as proton-sensitive nanoindicators. Owing to the selective quenching induced by the local pH variations of vesicular transport, FPSNICy3 and FPSNICy7 demonstrated excellent intracellular trafficking and provided sensitive optical indication of minute proton levels. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1169~1179 | - |
dc.relation.isPartOf | NANO RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Eun Bi Choi | - |
dc.contributor.googleauthor | Jihye Choi | - |
dc.contributor.googleauthor | Seo Ryung Bae | - |
dc.contributor.googleauthor | Hyun-Ouk Kim | - |
dc.contributor.googleauthor | Eunji Jang | - |
dc.contributor.googleauthor | Byunghoon Kang | - |
dc.contributor.googleauthor | Myeong-Hoon Kim | - |
dc.contributor.googleauthor | Byeongyoon Kim | - |
dc.contributor.googleauthor | Jin-Suck Suh | - |
dc.contributor.googleauthor | Kwangyeol Lee | - |
dc.contributor.googleauthor | Yong-Min Huh | - |
dc.contributor.googleauthor | Seungjoo Haam | - |
dc.identifier.doi | 10.1007/s12274-014-0597-6 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01916 | - |
dc.contributor.localId | A04359 | - |
dc.relation.journalcode | J02284 | - |
dc.identifier.eissn | 1998-0000 | - |
dc.subject.keyword | redox | - |
dc.subject.keyword | pH | - |
dc.subject.keyword | intracellular compartments | - |
dc.subject.keyword | organic quencher | - |
dc.subject.keyword | conducting polymer | - |
dc.subject.keyword | nanoindicator | - |
dc.contributor.alternativeName | Suh, Jin Suck | - |
dc.contributor.alternativeName | Huh, Yong Min | - |
dc.contributor.affiliatedAuthor | Suh, Jin Suck | - |
dc.contributor.affiliatedAuthor | Huh, Yong Min | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 8 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1169 | - |
dc.citation.endPage | 1179 | - |
dc.identifier.bibliographicCitation | NANO RESEARCH, Vol.8(4) : 1169-1179, 2015 | - |
dc.identifier.rimsid | 53934 | - |
dc.type.rims | ART | - |
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