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Disappearance of soft drusen and subsequent development of choroidal neovascularization following macular hole surgery: a case report

Authors
 Ji Hwan Lee  ;  Taekjune Lee  ;  Sung Chul Lee  ;  Christopher Seungkyu Lee 
Citation
 BMC OPHTHALMOLOGY, Vol.15 : 43, 2015 
Journal Title
BMC OPHTHALMOLOGY
Issue Date
2015
MeSH
Choroidal Neovascularization/diagnosis ; Choroidal Neovascularization/etiology* ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Fundus Oculi ; Humans ; Laser Coagulation/adverse effects* ; Macula Lutea/pathology ; Postoperative Complications ; Retinal Drusen/complications ; Retinal Drusen/surgery* ; Retinal Perforations/complications ; Retinal Perforations/surgery* ; Visual Acuity
Keywords
Drusen ; Choroidal neovascularization ; Macular hole ; Surgery
Abstract
BACKGROUND: Drusen are important risk factor for neovascular age-related macular degeneration (AMD) and have a dynamic nature as they can enlarge, newly form, or disappear over time. There have been few reports on drusen regression or choroidal neovascularization (CNV) development after macular hole surgery. We report, to our knowledge, the first case of both drusen regression and subsequent CNV development within 7 months of successful macular hole surgery.

CASE PRESENTATION: A 73-year-old woman presented with a stage 3 full-thickness macular hole and large, confluent soft macular drusen in the right eye and a neovascular age-related macular degeneration (AMD) in the fellow eye. Four months after the successful macular hole surgery, significant regression of drusen was seen, especially in the temporal area to the fovea. Three months later, the patient developed CNV and her best-corrected visual acuity decreased to 20/100, despite further regression of macular drusen.

CONCLUSIONS: Macular hole patients with macular soft drusen need to be carefully followed up after surgery for possible drusen regression and CNV development.
Files in This Item:
T201501420.pdf Download
DOI
10.1186/s12886-015-0029-8
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
Lee, Ji Hwan(이지환) ORCID logo https://orcid.org/0000-0003-1759-8195
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/140121
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