Diffuse unilateral subacute neuroretinitis in a healthy Korean male: the first case report in Korea

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MeSH: Animals ; Blindness/diagnosis ; Blindness/parasitology ; Eye Infections, Parasitic/diagnosis ; Eye Infections, Parasitic/parasitology ; Eye Infections, Parasitic/therapy* ; Fundus Oculi ; Humans ; Laser Therapy/methods ; Light Coagulation/methods ; Male ; Middle Aged ; Nematoda/pathogenicity* ; Republic of Korea ; Retinal Pigment Epithelium/parasitology* ; Retinal Pigment Epithelium/pathology ; Retinitis/diagnosis ; Retinitis/parasitology* ; Retinitis/therapy* ; Visual Acuity

Keywords: Diffuse Unilateral Subacute Neuroretinitis ; Laser Photocoagulation ; Nematode ; Zoonosis

Abstract: A 52-yr-old male was referred for progressive visual loss in the left eye. The decimal best-corrected visual acuity (BCVA) was 0.01. Fundus examination revealed diffuse retinal pigment epithelial degeneration, focal yellow-white, infiltrative subretinal lesion with fuzzy border and a live nematode within the retina. Diffuse unilateral subacute neuroretinitis (DUSN) was diagnosed and the direct laser photocoagulation was performed to destroy the live nematode. During eight months after treatment, BCVA gradually improved to 0.2 along with the gradual restoration of outer retinal layers on SD-OCT. We report on the first case of DUSN in Korea. DUSN should be included in the differential diagnosis of unexplained unilateral visual loss in otherwise healthy subjects.