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Synergistic effect of interaction between perceived health and social activity on depressive symptoms in the middle-aged and elderly: a population-based longitudinal study

Authors
 Sung-Youn Chun  ;  Kyu-Tae Han  ;  Seo Yoon Lee  ;  Chan Ok Kim  ;  Eun-Cheol Park 
Citation
 BMJ OPEN, Vol.5(3) : 007154, 2015 
Journal Title
 BMJ OPEN 
Issue Date
2015
MeSH
Aged ; Aged, 80 and over ; Depression/psychology* ; Female ; Health Status* ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Models, Psychological ; Psychiatric Status Rating Scales ; Republic of Korea ; Rural Population ; Social Participation/psychology* ; Urban Population
Keywords
GERIATRIC MEDICINE ; MENTAL HEALTH ; PUBLIC HEALTH ; SOCIAL MEDICINE
Abstract
OBJECTIVE: To examine the synergistic effect of interaction between perceived health and social activity on depressive symptoms. METHODS: We investigated whether the interaction between perceived health and social activity has a synergistic effect on depressive symptoms in the middle-aged and elderly using data from 6590 respondents aged 45 and older in the Korean Longitudinal Study on Aging (KLoSA), 2006-2012. A generalised linear mixed-effects model was used to investigate the association in a longitudinal data form. Depressive symptoms were measured using the Center for Epidemiological Studies Depression 10 Scale (CES-D10). Perceived health and level of social activity were categorical variables with three values. Participation in six social activities was assessed. RESULTS: Interactions between perceived health status and social activity were statistically significant for almost all social activity/perceived health combinations. Addition of the interaction term significantly decreased CES-D10 scores, confirming the synergistic effect of the interaction between perceived health status and social activity ('normal×moderate', β=-0.1826; 'poor×moderate', β=-0.5739; 'poor×active', β=-0.8935). In addition, we performed stratified analyses by region: urban or rural. In urban respondents, the additional effect of the interaction term decreased CES-D10 scores and all social activity/perceived health combinations were statistically significant ('normal×moderate', β=-0.2578; 'normal×active', β=-0.3945; 'poor×moderate', β=-0.5739; 'poor×active', β=-0.8935). In rural respondents, only one social activity/perceived health combination was statistically significant, and the additional effect of the interaction term showed no consistent trend on CES-D10 scores. CONCLUSIONS: The interaction between perceived health and social activity has a synergistic effect on depressive symptoms; the additional effect of the interaction term significantly decreased CES-D10 scores in our models.
Files in This Item:
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DOI
10.1136/bmjopen-2014-007154
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
Yonsei Authors
Park, Eun-Cheol(박은철) ORCID logo https://orcid.org/0000-0002-2306-5398
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139604
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