Cited 9 times in
A multistep photothermic-driven drug release system using wire-framed Au nanobundles
DC Field | Value | Language |
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dc.contributor.author | 허용민 | - |
dc.date.accessioned | 2016-02-04T10:58:42Z | - |
dc.date.available | 2016-02-04T10:58:42Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2192-2640 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139397 | - |
dc.description.abstract | Here, wire-framed Au nanobundles (WNBs), which consist of randomly oriented and mutually connected Au wires to form a bundle shape, are synthesized. In contrast to conventional nanoparticles (spheres, rods, cubes, and stars), which exhibit nanostructure only on the surface, cross-sectional view image shows that WNBs have nanostructures in a whole volume. By using this specific property of WNBs, an externally controllable multistep photothermic-driven drug release (PDR) system is demonstrated for in vivo cancer treatment. In contrast to conventional nanoparticles that encapsulate a drug on their surface, WNBs preserve the drug payload in the overall inner volume, providing a drug loading capacity sufficient for cancer therapy. An improved in vivo therapeutic efficacy of PDR therapy is also demonstrated by delivering sufficient amount of drugs to the target tumor region. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 255~263 | - |
dc.relation.isPartOf | ADVANCED HEALTHCARE MATERIALS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Absorption, Physicochemical | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cell Line, Tumor | - |
dc.subject.MESH | Drug Delivery Systems/methods* | - |
dc.subject.MESH | Gold/chemistry* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Light* | - |
dc.subject.MESH | Metal Nanoparticles/chemistry* | - |
dc.subject.MESH | Metal Nanoparticles/ultrastructure | - |
dc.subject.MESH | Mice, Inbred BALB C | - |
dc.subject.MESH | Mice, Nude | - |
dc.subject.MESH | Microscopy, Fluorescence | - |
dc.subject.MESH | Spectroscopy, Near-Infrared | - |
dc.subject.MESH | Temperature* | - |
dc.title | A multistep photothermic-driven drug release system using wire-framed Au nanobundles | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Doyeon Bang | - |
dc.contributor.googleauthor | Taeksu Lee | - |
dc.contributor.googleauthor | Jihye Choi | - |
dc.contributor.googleauthor | Yeonji Park | - |
dc.contributor.googleauthor | Eunkyoung Kim | - |
dc.contributor.googleauthor | Yong-Min Huh | - |
dc.contributor.googleauthor | Seungjoo Haam | - |
dc.identifier.doi | 10.1002/adhm.201400197 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04359 | - |
dc.relation.journalcode | J00042 | - |
dc.identifier.eissn | 2192-2659 | - |
dc.identifier.pmid | 25044601 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/adhm.201400197/abstract | - |
dc.subject.keyword | cancer therapy | - |
dc.subject.keyword | controlled release | - |
dc.subject.keyword | drug delivery | - |
dc.subject.keyword | nanoparticles | - |
dc.subject.keyword | nanostructures | - |
dc.contributor.alternativeName | Huh, Yong Min | - |
dc.contributor.affiliatedAuthor | Huh, Yong Min | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 4 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 255 | - |
dc.citation.endPage | 263 | - |
dc.identifier.bibliographicCitation | ADVANCED HEALTHCARE MATERIALS, Vol.4(2) : 255-263, 2015 | - |
dc.identifier.rimsid | 55369 | - |
dc.type.rims | ART | - |
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