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Functional genomic and metagenomic approaches to understanding gut microbiota-animal mutualism

Authors
 Sang Sun Yoon  ;  Eun-Kyoung Kim  ;  Won-Jae Lee 
Citation
 CURRENT OPINION IN MICROBIOLOGY, Vol.24 : 38-46, 2015 
Journal Title
CURRENT OPINION IN MICROBIOLOGY
ISSN
 1369-5274 
Issue Date
2015
MeSH
Animals ; Gastrointestinal Microbiome* ; Metagenomics* ; Symbiosis
Abstract
Accumulating data sets of gut microbiome by next-generation sequencing allow us to gain a comprehensive view of the functional diversity of the gut-associated metagenome. However, many microbiome functions are unknown and/or have only been predicted, and may not necessarily reflect the in vivo function within a gut niche. Functional genomic and metagenomic approaches have been successfully applied to broaden the understanding of invertebrate and vertebrate gut microbiome involved in diverse functions, including colonization ability, nutritional processing, antibiotic resistance, microbial physiology and metabolism, and the modulation of the host physiology. In this review, we discuss the recent knowledge obtained from the study of functional genomics and metagenomics of the animal intestine and its potential values for understanding gut microbiota-animal mutualism.
Full Text
http://www.sciencedirect.com/science/article/pii/S1369527415000089
DOI
10.1016/j.mib.2015.01.007
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Microbiology (미생물학교실) > 1. Journal Papers
Yonsei Authors
Yoon, Sang Sun(윤상선) ORCID logo https://orcid.org/0000-0003-2979-365X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139275
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