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The association between platelet count and metabolic syndrome in children and adolescents.

Authors
 Hyoung Ji Lim  ;  Min Seok Seo  ;  Yong Jae Lee  ;  Youn Ho Shin  ;  Kyu Earn Kim  ;  Jae Yong Shim 
Citation
 Platelets, Vol.26(8) : 758-763, 2015 
Journal Title
 Platelets 
ISSN
 0953-7104 
Issue Date
2015
Abstract
The goal of this study was to evaluate the association between platelet count and metabolic syndrome (MetS) in children and adolescents in Korea. This study included data from 2228 subjects (1201 boys and 1027 girls) who participated in the 2010-2012 Korean National Health and Nutrition Examination Survey (KNHANES-V). We used the modified National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) criteria to define MetS. Odds ratios (95% confidence intervals [CIs]) for MetS were calculated with a multiple logistic regression analysis after adjusting for confounding factors across platelet count quartiles. The overall prevalence of MetS according to the modified NCEP-ATP III criteria was 4.9% (±0.7%) in boys and 5.7% (±0.9%) in girls. The prevalence of MetS significantly increased with increasing platelet quartiles in both boys and girls. In a multiple logistic regression analysis, the adjusted ORs (95% CIs) for the highest vs. the lowest quartile were 5.03 (1.30-19.48) in boys and 4.08 (1.20-13.93) in girls after adjusting for age and total cholesterol. CONCLUSIONS: Higher platelet count was associated with increased prevalence and risk of MetS in children and adolescents.
Full Text
http://www.tandfonline.com/doi/full/10.3109/09537104.2014.995613#.VlaoqHbhDcs
DOI
10.3109/09537104.2014.995613
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
김규언(Kim, Kyu Earn)
서민석(Seo, Min Seok)
심재용(Shim, Jae Yong) ORCID logo https://orcid.org/0000-0002-9561-9230
이용제(Lee, Yong Jae) ORCID logo https://orcid.org/0000-0002-6697-476X
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/139119
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