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Comparison of non-ablative and ablative fractional laser treatments in a postoperative scar study.

 Jung U Shin  ;  Dorjsuren Gantsetseg  ;  Jin Young Jung  ;  Inhee Jung  ;  Sungsik Shin  ;  Ju Hee Lee 
 LASERS IN SURGERY AND MEDICINE, Vol.41(10) : 741-749, 2014 
Journal Title
Issue Date
Adult ; Cicatrix/etiology* ; Cicatrix/pathology ; Cicatrix/surgery* ; Female ; Follow-Up Studies ; Humans ; Laser Therapy/instrumentation* ; Lasers, Gas/therapeutic use* ; Lasers, Solid-State/therapeutic use* ; Middle Aged ; Patient Satisfaction ; Thyroidectomy/adverse effects* ; Treatment Outcome ; Young Adult
scarring ; split-scar study ; thyroidectomy
BACKGROUND AND OBJECTIVE: Postoperative scarring after thyroidectomy is a problem for both patients and clinicians. Recently, both non-ablative and ablative fractional laser (NFL and AFL) systems have attracted attention as potential therapies for the revision of thyroidectomy scars. The present split-scar study was designed to directly compare the efficacy of these two methods for the treatment of post-thyroidectomy scars. STUDY DESIGN/MATERIALS AND METHODS: Twenty females (mean age 42.1 years, range 22-55) with scarring 2-3 months post-thyroidectomy were enrolled in the study. One half of the scar (chosen at random) was treated with NFL and the other half was treated with AFL. In each case, two treatments were given at 2-month intervals. Clinical photographs were taken at baseline, before each treatment, and at the final 3-month evaluation. Independent clinician grading of improvement and patient satisfaction were measured on a quartile scale. Color (erythema and melanin indices) and scar hardness were measured at baseline and at three months post-treatment with a dermaspectrometer and durometer, respectively. RESULTS: The mean clinical improvement grades for AFL and NFL were highly similar, 2.45 ± 0.99 and 2.35 ± 0.85, respectively, without statistical significance (P = 0.752). However, NFL treatment resulted in statistically significant changes in erythema and pigmentation (P = 0.035 and P = 0.003, respectively), and skin hardness was significantly reduced after AFL treatment (P = 0.026). CONCLUSIONS: Clinical improvement was not significantly different between the two systems; however, AFL was better at reducing scar hardness whereas NFL was superior for lightening color. These data suggest that a study assessing the feasibility of a combined approach for the revision of post-thyroidectomy scarring might be warranted.
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1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jung U(신정우) ORCID logo https://orcid.org/0000-0001-5259-6879
Lee, Ju Hee(이주희) ORCID logo https://orcid.org/0000-0002-1739-5956
Jung, Inhee(정인희)
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