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Prevalence of and risk factors associated with dry eye: the Korea National Health and Nutrition Examination Survey 2010-2011

 Ji Min Ahn  ;  Seung Hyun Lee  ;  Tyler Hyung Taek Rim  ;  Ryoung Jin Park  ;  Hong Seok Yang  ;  Tae im Kim  ;  Kyung Chul Yoon  ;  Kyoung Yul Seo 
 AMERICAN JOURNAL OF OPHTHALMOLOGY, Vol.158(6) : 1205-7, 2014 
Journal Title
Issue Date
Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Dry Eye Syndromes/epidemiology* ; Dry Eye Syndromes/psychology ; Female ; Health Status ; Humans ; Male ; Middle Aged ; Nutrition Surveys/statistics & numerical data ; Odds Ratio ; Prevalence ; Quality of Life/psychology ; Republic of Korea/epidemiology ; Risk Factors ; Rural Population/statistics & numerical data ; Sex Distribution ; Sickness Impact Profile ; Urban Population/statistics & numerical data ; Young Adult
PURPOSE: To investigate the prevalence of and risk factors associated with dry eye syndrome (DES) in South Korea.

DESIGN: Cross-sectional study.

METHODS: In 2010 and 2011, 11,666 subjects, ranging in age from 19 to 95, were randomly selected as nationally representative participants in the Korea National Health and Nutrition Examination Survey (KNHANES). Subjects were divided into 2 groups: 1 with clinically diagnosed DES and 1 with symptoms of dry eye. We determined the prevalence of and risk factors for dry eyes in a Korean population. Health-related quality of life (HRQoL), measured by the EuroQoL-5 dimension (EQ-5D), was evaluated in patients with dry eyes.

RESULTS: The mean age was 49.9 years. The overall prevalence of diagnosed DES was 8.0% (95% confidence interval [CI], 7.3% to 8.7%), and of dry eye symptoms the prevalence was 14.4% (95% CI, 13.1 to 15.7). Age (adjusted odds ratio [aOR] = 1.8, 1.6), female (aOR = 2.8, 1.9); history of eye surgery (aOR = 2.6, 2.2); stress (aOR = 1.7, 1.6); thyroid disease (aOR = 1.7, 1.5); and high education level (aOR = 1.6, 1.5) were common risk factors in the groups. Subjects who had undergone ptosis, cataract or refractive surgery were more likely to have dry eye than subjects with no history of eye surgery. Means of pain and anxiety dimensions in the EQ-5D and the Euro Quality of Life Visual Analog Scale (EQ-VAS) were significantly higher in the group with diagnosed DES than in the normal group.

CONCLUSIONS: The risk factors were mostly similar in both groups. It is thought there are more patients with DES who have not been diagnosed by doctors. Doctors should identify whether a patient has any risk factors for dry eye. Patients need to be educated about the modifiable factors of DES.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Tae-Im(김태임) ORCID logo https://orcid.org/0000-0001-6414-3842
Seo, Kyoung Yul(서경률) ORCID logo https://orcid.org/0000-0002-9855-1980
Rim, Tyler Hyungtaek(임형택)
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