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Krypton-enhanced ventilation CT with dual energy technique: experimental study for optimal krypton concentration

DC FieldValueLanguage
dc.contributor.author이명수-
dc.contributor.author이미정-
dc.contributor.author이혜정-
dc.contributor.author정용은-
dc.contributor.author홍새롬-
dc.date.accessioned2015-12-28T10:58:15Z-
dc.date.available2015-12-28T10:58:15Z-
dc.date.issued2014-
dc.identifier.issn0190-2148-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/138415-
dc.description.abstractPURPOSE/AIM OF THE STUDY: To assess the feasibility of krypton-enhanced ventilation CT using dual energy (DE) technique for various krypton concentrations and to determine the appropriate krypton concentration for DE ventilation CT through an animal study. MATERIALS AND METHODS: Baseline DECT was first performed on seven New Zealand white rabbits. The animals were then ventilated using 20%, 30%, 40%, 50%, 60%, to 70% krypton concentration, and DECT was performed for each concentration. Krypton extraction was performed through a workstation, and results were displayed on a color map. Overlay Hounsfield unit (HU) values were obtained by two observers in consensus readings. A linear mixed model was used to correlate overlay HU values and krypton concentrations. Visual assessments of the homogeneity of krypton maps were also performed. RESULTS: Mean overlay HU values according to krypton concentration were as follows; 20% krypton, 1.68 ± 5.15; 30% krypton, 3.73 ± 5.93; 40% krypton, 6.92 ± 5.51; 50% krypton, 10.88 ± 5.17; 60% krypton, 14.54 ± 4.23; and 70% krypton, 18.79 ± 3.63. We observed a significant correlation between overlay HU values on krypton maps and krypton concentrations (P < .001). For the krypton color maps, all observers determined universal enhancement on the 70% krypton map for all animals. CONCLUSION: It is feasible to evaluate lung ventilation function using DECT with a krypton concentration of at least 70%.-
dc.description.statementOfResponsibilityopen-
dc.format.extent439~446-
dc.relation.isPartOfEXPERIMENTAL LUNG RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHFeasibility Studies-
dc.subject.MESHKrypton*/administration & dosage-
dc.subject.MESHLung/diagnostic imaging*-
dc.subject.MESHMultidetector Computed Tomography/methods*-
dc.subject.MESHPulmonary Ventilation*-
dc.subject.MESHRabbits-
dc.titleKrypton-enhanced ventilation CT with dual energy technique: experimental study for optimal krypton concentration-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorYong Eun Chung-
dc.contributor.googleauthorSae Rom Hong-
dc.contributor.googleauthorMi-Jung Lee-
dc.contributor.googleauthorMyungsu Lee-
dc.contributor.googleauthorHye-Jeong Lee-
dc.identifier.doi10.3109/01902148.2014.946630-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03320-
dc.contributor.localIdA02774-
dc.contributor.localIdA02751-
dc.contributor.localIdA03662-
dc.contributor.localIdA04396-
dc.relation.journalcodeJ00871-
dc.identifier.eissn1521-0499-
dc.identifier.pmid25153921-
dc.identifier.urlhttp://www.tandfonline.com/doi/full/10.3109/01902148.2014.946630-
dc.subject.keyworddual energy CT-
dc.subject.keywordkrypton-
dc.subject.keywordlung function-
dc.subject.keywordmaterial decomposition-
dc.subject.keywordventilation-
dc.contributor.alternativeNameLee, Myung Su-
dc.contributor.alternativeNameLee, Mi Jung-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameChung, Yong Eun-
dc.contributor.alternativeNameHong, Sae Rom-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.contributor.affiliatedAuthorLee, Mi Jung-
dc.contributor.affiliatedAuthorLee, Myung Su-
dc.contributor.affiliatedAuthorChung, Yong Eun-
dc.contributor.affiliatedAuthorHong, Sae Rom-
dc.rights.accessRightsfree-
dc.citation.volume40-
dc.citation.number9-
dc.citation.startPage439-
dc.citation.endPage446-
dc.identifier.bibliographicCitationEXPERIMENTAL LUNG RESEARCH, Vol.40(9) : 439-446, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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