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Synthesis and Anticancer Activity of Novel Deoxoartemisinin-Glycolipid Hybrids

DC Field Value Language
dc.contributor.author김기림-
dc.contributor.author박광균-
dc.contributor.author정원윤-
dc.date.accessioned2015-12-28T10:52:14Z-
dc.date.available2015-12-28T10:52:14Z-
dc.date.issued2014-
dc.identifier.issn0009-2363-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/138204-
dc.description.abstractThe practical synthesis and anticancer activity of novel deoxoartemisinin-glycolipid hybrids, which incorporate two drugs into a single molecule and can impact multiple targets simultaneously are presented. These hybrids exhibited potent in vitro anticancer activity against several human cancer cell lines. The deoxoartemisinin-glycolipid hybrids generally demonstrated better anticancer activity than either artemisinin or daumone alone and cisplatin.-
dc.description.statementOfResponsibilityopen-
dc.format.extent446~453-
dc.relation.isPartOfCHEMICAL & PHARMACEUTICAL BULLETIN-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAntineoplastic Agents/chemical synthesis*-
dc.subject.MESHAntineoplastic Agents/chemistry-
dc.subject.MESHAntineoplastic Agents/pharmacology*-
dc.subject.MESHArtemisinins/chemistry-
dc.subject.MESHArtemisinins/pharmacology*-
dc.subject.MESHCell Line, Tumor-
dc.subject.MESHCell Proliferation/drug effects-
dc.subject.MESHCell Survival/drug effects-
dc.subject.MESHDose-Response Relationship, Drug-
dc.subject.MESHDrug Screening Assays, Antitumor-
dc.subject.MESHGlycolipids/chemistry-
dc.subject.MESHGlycolipids/pharmacology*-
dc.subject.MESHHumans-
dc.subject.MESHMCF-7 Cells-
dc.subject.MESHMolecular Structure-
dc.subject.MESHStructure-Activity Relationship-
dc.titleSynthesis and Anticancer Activity of Novel Deoxoartemisinin-Glycolipid Hybrids-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral Biology (구강생물학)-
dc.contributor.googleauthorDongguk Min-
dc.contributor.googleauthorMinkyu Kim-
dc.contributor.googleauthorJérémy Ricci-
dc.contributor.googleauthorSora Jung-
dc.contributor.googleauthorKirim Kim-
dc.contributor.googleauthorWon Yoon Chung-
dc.contributor.googleauthorKwang Kyun Park-
dc.contributor.googleauthorMankil Jung-
dc.identifier.doi10.1248/cpb.c14-00036-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00333-
dc.contributor.localIdA01429-
dc.contributor.localIdA03676-
dc.relation.journalcodeJ00509-
dc.identifier.eissn1347-5223-
dc.identifier.pmid24614158-
dc.subject.keywordanticancer activity-
dc.subject.keywordoral squamous carcinoma-
dc.subject.keyworddeoxoartemisinin-
dc.subject.keywordglycolipid hybrid-
dc.contributor.alternativeNameKim, Ki Rim-
dc.contributor.alternativeNamePark, Kwang Kyun-
dc.contributor.alternativeNameChung, Won Yoon-
dc.contributor.affiliatedAuthorKim, Ki Rim-
dc.contributor.affiliatedAuthorPark, Kwang Kyun-
dc.contributor.affiliatedAuthorChung, Won Yoon-
dc.citation.volume62-
dc.citation.number5-
dc.citation.startPage446-
dc.citation.endPage453-
dc.identifier.bibliographicCitationCHEMICAL & PHARMACEUTICAL BULLETIN, Vol.62(5) : 446-453, 2014-
dc.identifier.rimsid47219-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실) > 1. Journal Papers
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