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Consumption of legumes accelerates weight loss accompanied by regulation of adiponectin and 8-epi-PGF2α

Other Titles
 두류섭취가 adiponectin과 8-epi-PGF2α 조절을 동반한 체중감소 촉진에 미치는 영향 
Authors
 김아람 
Issue Date
2014
Description
Dept. of Science for Aging/석사
Abstract
Objectives: The purpose of this study was to examine the effect of legume on body weight in obese subject.Methods: Randomized controlled study of 12 weeks with 383 participants (body mass index ≥ 25 kg/m2) was enrolled for the study. The intervention program consisted of replacing 1/3 refined rice intake with legumes three times per day as a carbohydrate source in high fat diet group while low fat diet group were recommended to eat as their usual diet.Results: In high fat diet group, intake of energy and carbohydrate were lower, while intake of fat and protein were higher. Mean weight loss at 12 weeks was 2.87±0.21 kg and 0.17±0.11 kg in the high fat diet group and low fat diet group, respectively, and was significantly different between groups (P<0.001). HDL-cholesterol and adiponectin were increased, while glucose, insulin, triglyceride, HOMA-IR index, and 8-epi-PGF2α were decreased at 12 weeks in the high fat diet group compared with baseline.Conclusion: Consumption of legumes may accelerate weight loss accompanied by regulation of adiponectin and 8-epi-PGF2α in obese subjects.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Others (기타) > 2. Thesis
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/136584
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