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Space maintenance of a cross-linked collagenated porcine bone grafted without barrier membrane in one-wall intrabony defects

Other Titles
 성견 일벽성 골내 결손부에서 교차결합된 교원질과 혼합된 돼지 유래 이종골의 공간 유지능에 관한 연구 
Issue Date
Dept. of Dental Science/석사
The aim of this study was to evaluate the effect of a cross-linked collagenated porcine bone (CPB) in surgically prepared one-wall intrabony defects in dogs.Buccolingually opened, one-wall, box type, intrabony periodontal defects (4 × 5 mm) were prepared bilaterally at the mesial side of the mandibular fourth premolars in beagle dogs (N = 5). Block-type CPB (4 × 5 × 5 mm) was placed alternatively on either the left or right side for the CPB group, the opposite site served as sham-surgery controls. After 3 months, block specimens were obtained. Microcomputed tomographic and histological analysis were performed.The mean of bone regeneration (BR) and cementum regeneration (CR) of experimental group were lower than those of sham-surgery control group. Much of the porcine bone particles were located under the floor of the defect and were sequestered from pristine bone. It can be concluded that CPB can be localized within the defect for wound healing period by cross-linking, however, applying CPB alone without barrier membrane may not be effective to promote periodontal regeneration in noncontained type defects.
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2. College of Dentistry (치과대학) > Others (기타) > 2. Thesis
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