The effect of barrier membrane on lateral onlay graft in dogs

Abstract

ABSTRACTThe effect of barrier membrane on lateral onlay graft in dogsGeun Lee, D.D.S.Department of Dental ScienceGraduate School, Yonsei University(Directed by Professor Jung-Kiu Chai, D.D.S., M.S.D., Ph.D.)Objectives: The objective of this study was to evaluate the role of a bioresorbable collagen membrane (CM) in conjunction with bovine hydroxyapatite incorporated with collagen matrix (BHC) for lateral onlay graft in dogs.Materials and methods: The first, second and third premolars on right upper jaw were extracted and healed for 2 months in five mongrel dogs (N=5). After flap reflection on the buccal alveolar ridge of maxillary premolar area, two BHC were placed with (membrane group) or without (non membrane group) coverage of CM, respectively. After 8 weeks of healing, the animals were sacrificed and specimens were collected for histometric analysis.Results: After 8 weeks of healing period, CM still remains as collagen network and serves as a barrier. The Membrane group was significantly higher in all histormetric parameters representing the quantity and quality of bone regeneration than the Non-membrane group (p<0.05).Conclusion: Results suggest that the additional use of a barrier membrane may lead to an increase in new bone formation and bone quality than bone graft alone in lateral onlay graft. These findings suggest that the use of CM in lateral onlay graft can enhance quantity and quality of bone regeneration.