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Dimensional change of the healed periosteum on surgically created defect

Other Titles
 외과적 결손부 형성 후 치유된 골막의 체적 변화 
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Dept. of Dental Science/석사
[영문]The final goal of regenerative periodontal therapy is to restore the structure and function of the periodontium destroyed or lost due to periodontitis. However, the role of periosteum in periodontal regeneration was relatively neglected while bone repair in the skeleton occurs as a result of a significant contribution from the periosteum. The aim of this study is to understand the dimensional change of periosteum and compare the native periosteum with the repaired periosteum after elevating flap or after surgical intervention with flap elevation. Buccal and lingual mucoperiosteal flaps were reflected to surgically create critical-size, “box-type” (4 mm width, 5 mm depth), one-wall, intrabony defects at the distal aspect of the 2nd and the mesial aspect of the 4th mandibular premolars in the right and left jaw quadrants. Animals were sacrificed after 24 weeks. The conclusions from this study are as follows. 1. Thickness of periosteum showed difference as follows(p<0.05);Control group (0.45±0.22mm) had the greatest thickness followed by flap only group (0.36±0.07mm) and defect formation group (0.26±0.03mm).2. Thickness of gingival tissue showed difference as follows(p<0.05);Defect formation group (3.15±0.40mm) had the greatest thickness followed by flap only group (2.02±0.25mm) and control group (1.88±0.27mm).3. Higher cellular activity was observed in defect formation group and flap only group than control group.4. The number of blood vessels was higher in defect formation group than control group.In conclusion, prolonged operation with increased surgical trauma seems to decrease the thickness of repaired periosteum and increase the thickness of gingiva. More blood vessels and high cellular activity were observed in defect formation group.
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2. College of Dentistry (치과대학) > Others (기타) > 2. Thesis
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