4. 연령별 분리수는 9세이하군에서 50.7 %로 가장 많았고 60세 이상에서도 8.0% 로 비교적 많았다. 1명의 신생아는 패혈증이 동반된 수막염이었는데 이로 인하여 사망하였다. 성별 분리수는 남자에서 다소 많았다.
5.대부분의 환자들은 조직손상, 종양, 결핵, 당뇨병등 세균의 감염을 초래하기 쉬운 기존질환을 가지고 있었다.
이 연구의 결과로 β-용혈성 연쇄구균중 B, C 및 G군은 호흡기계에서는 감염을 일으키는 일이 적지만, 호흡기 이외의 부위에서는 감염의 원인균으로서 분리되는 일이 많고, 기존질환이 있는 환자는 감염이 되기 쉬우며 중독한 경과를 밟기도 하므로 종래의 bacitracin법에 의한 A군만의 동정으로는 불충분하며 적어도 B, C 및 G혈청군의 동정도 필요하다는 결론을 얻었다.
A study on the infection due to group B. C and G β- hemolytic streptococci
Chol Young Sook
Department of Medical Science The Graduate School Yonsei university
(Directed by Prof. Samuel Y. Lee. M.D.)
Streptococci, Pathogenic to human subjects, are mostly β-hemolytic and generally
belong to groups A and D. organisms belonging to B. C. and G have long been known
to cause infections. but their clinical importance has not been recognized until
quite recently. The incidence of fatal neonatal infections of group B has been
increasing particularly during the decade. However, there has been only a few
reports on group B, C, and G infection in Korea.
This study was made to determine serological group of clinical isolate of
β-hemolytic streptococci by coagglutination method and to clarify the B, C, and G
infection in a Korea.
β-hemolytic streptococci isolated from Yonsei Medical Center specimen during
August 1979-October 1980 were studied and the following results were obtained.
1. A total of 414 isolates were obtained and their groups were: A 19.1%, B 6.3%,
C 11.4%, and nongroupable 49.5%.
2. Groups B, C, and G were most frequently isolated from the respiratory tract
specimens. Excluding respiratory sources, group B was mainly isolated from the
urogenital tract, and group G from various wounds.
3. Among the l26 patient, who were categorized as having definite infections, 12
yieled group B, 3group C and 27 group G organisms. There were 8 cases each of the
respiratory and urogenital tract infections, on 26 infections on various other
sites.
4. From patients under 10 years of age, 50.7% of B, C, and G organisms were
isolated. 8.0% of the culture were isolated from patients 60 years and over.
There was a fatal neonatal meningitis and septicemia due to group B organism. the
organisms were isolated more frequently from male patients .
5. Majority of the patients who yielded the organisms were found to have
underlying diseases such as tissue injury neoplasm, tuberculosis and diabetes
mellitus.
It is concluded that group B, C, and G streptococci cause respiratory infection
not frequently, but they often invade other sites. patients with underlying disease
are prone to be infected by the organisms and some of them can be fatal. Therefore
it is important to identify not only group A but also B, C, and G organisms.
[영문]
Streptococci, Pathogenic to human subjects, are mostly β-hemolytic and generally belong to groups A and D. organisms belonging to B. C. and G have long been known to cause infections. but their clinical importance has not been recognized until quite recently. The incidence of fatal neonatal infections of group B has been increasing particularly during the decade. However, there has been only a few reports on group B, C, and G infection in Korea.
This study was made to determine serological group of clinical isolate of β-hemolytic streptococci by coagglutination method and to clarify the B, C, and G infection in a Korea.
β-hemolytic streptococci isolated from Yonsei Medical Center specimen during August 1979-October 1980 were studied and the following results were obtained.
1. A total of 414 isolates were obtained and their groups were: A 19.1%, B 6.3%, C 11.4%, and nongroupable 49.5%.
2. Groups B, C, and G were most frequently isolated from the respiratory tract specimens. Excluding respiratory sources, group B was mainly isolated from the urogenital tract, and group G from various wounds.
3. Among the l26 patient, who were categorized as having definite infections, 12 yieled group B, 3group C and 27 group G organisms. There were 8 cases each of the respiratory and urogenital tract infections, on 26 infections on various other
sites.
4. From patients under 10 years of age, 50.7% of B, C, and G organisms were isolated. 8.0% of the culture were isolated from patients 60 years and over.
There was a fatal neonatal meningitis and septicemia due to group B organism. the organisms were isolated more frequently from male patients .
5. Majority of the patients who yielded the organisms were found to have underlying diseases such as tissue injury neoplasm, tuberculosis and diabetes mellitus.
It is concluded that group B, C, and G streptococci cause respiratory infection not frequently, but they often invade other sites. patients with underlying disease are prone to be infected by the organisms and some of them can be fatal. Therefore
it is important to identify not only group A but also B, C, and G organisms.