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월경조절법의 임상적 연구 및 Pregnosticon Dri-Dot 임신반응검사의 평가

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 (A) clinical study on menstrual regulation and an evaluation of the pregnosticon dri-dot test in early pregnancy 
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The present study is undertaken to analyze the socio-demographic characteristics and fertility profile of the menstrual regulation acceptors, to ecaluate the safety and effectiveness of menstrual regulation and to evaluate the accuracy of the Pregnosticon Dri-Dot test on the women who were amenorrheic from 35-50 days. A total of 154 cases were menstrually regulated and 59 cases were tested using the Pregnosticon Dri-Dot test and sent the aspirated uterine contents for tissue examination to document pregnancy at the Yonsei Medical Center Fertility Control Room from July 1 to October 15, 1974.

Menstrual regulation(M.R.) refers to treatment of missed menstrual periods before confirming evidence or pregnancy is available. The procedure consists of a simple aspiration of the endometrium with or without products of conception, according to

the underlying cause. For this a 4-8㎜ plastic cannula is introduced without dilatation of the cervix and vaccum provided by evacuating air from a 50 cc. syringe. The Pregnosticon Dri-Dot test is a latex agglutination-inhibition slide test for presumptive diagnosis of pregnancy which has been newly developed, a relatively more accurate test than other pregnancy tests developed in the past.

The result of this study shows menstrual regulation acceptors were a selected group of the population in Seoul. The median age was 33 years and median parity was 2.8. Therefore 91 percent of the menstrual regulation acceptors were between 25 to 39 years of age and 65 percent of them had had 2 to 3 living children. Their

education level was much higher than the general population in Seoul, as 74.8 percent of those women had completed 10 or more years of schooling, while 8.4 percent of 25 to 49 years old women in Seoul completed 10 ot more years schooling according to 1970 Census statistics. More than half of the menstrual regulation

acceptors responded that their ideal number of living children was three. There were no major complications, Failure rate of menstrual regulation was 1.3%. So menstrual regulation is a safe, effective, simple and acceptable low-cost procedure for preventing unwanted pregnancies. After 35 days of amenorrhea more than 50 percent of the patients were documented to be pregnant. The incidence of documented pregnancy increased with a positive Pregnosticon Dri-Dot test were documented to be pregnant. The probability of obtaining a negative test in a pregnant women

decreases with increasing length of amenorrhea. Even at 42 days of amenorrhea, 25 percent of those patients with a negative pregnancy test were documented to be pregnant. It was not until 45 days of amenorrhea that the false negative rate of the test declined to below 3.7 percent.
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