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Argon 레이저홍채절제술후의 일시적 안압상승에 관한 실험적 연구

Other Titles
 (The) transient change of intraocular pressure following argon laser iridotomy in rabbits 
Authors
 김관식 
Issue Date
1986
Description
의학과/석사
Abstract
[한글]

빛의 에너지를 이용한 녹내장의 치료는 1946년 Meyer-chwickerath가 Xenon arc를 사용 처음 시도한 이래 녹내장치료를 위한 여러 가지 에너지원과 기술들이 개발되어 왔다.

Xenon arc에 의한 홍채절제술은 성공하였지만 과도한 열과 색소분산에 의하여 널리 인정받지는 못하였다.

Argon 레이저광용고술은 1968년 L'Esperance에 의하여 여러 맥락막, 망막질환의 치료에 처음 사용되었다.

과거 수년간 argon 레이저는 원발성 및 속발성 협우각형녹내장의 치료법으로 보편화 되었으나 레이저조사시 수정체 및 안압에 미치는 영향등의 합병증이 확실히 규명되어 있지는 않다.

본 연구에서 argon 레이저홍채절제술을 유색과 무색의 가토안에 시행한 후 Perkins tonometer와 세격등현미경을 이용 초기의 일시적인 안압상승을 관찰하여 다음과 같은 결론을 얻었다.

1. 레이저로 홍채절제술이 성공될 때 까지의 조사벙법에 따른 조사횟수 유색가토에서 장시간조사방법(long burn technique)이 단시간 조사방법(short burn technique)에 비하여 조사횟수는 적었으며 조사방법별 평균조사횟수는 장시간조사방법으로는

194회, 단시간 조사벙법으로는 942회였다.

2. Argon 레이저홍채절제술후 레이저에너지와 술후 최고안압과의 상관관계

1) Argon 레이저홍채절제술후 최고안압은 24mmHg, 최저안압은 8mmHg였으며 조사된 레이저에너지와는 상관관계가 없었다.

3. Argon 레이저홍채절제술후 유색과 무색가토에서 안압의 변호

1) 유색가토에서는 술후 30분경 안압이 가장 많이 상승하였고 무색가토에서는 술후 안압의 변화가 없었다.

2) 유색가토에서 장시간조사방법이 단시간조사방법에 비하여 안압이 더 많이 상승하였다.

4. Argon 레이저홍채절제술후의 홍채염의 정도

1) 유색가토에서는 술후 1일에 홍채염이 가장 심하게 나타났으며 무색가토에서는 술후 홍채염이 나타나지 않았다.

2) 유색가토에서 장시간조사방법이 단시간조사방법에 비하여 술후의 홍채염이 더 심하게 나타났다.



[영문]The transient change of intraocular pressure following argon laser iridotomy in rabbits



Kwan Sik Kim

Department of Medical Science The Graduate School Yonsei University

(Directed by Professor Ouk Choi, M.D.)



The use of focused light energy in the anterior segment for glaucoma therapy has been attributed to Meyer-Schwickerath, who performed iridotomies using a Zeiss light (xenon arc) coagulator in 1956.

Since that time several procedures and energy sources have been developed th aid in the therapy of glaucoma. Although the xenon arc did succeed in making iridotomies, the excessive heat ant dispersion of pigment limited the value of this technique.

Argon laser photocoagulation has been used successfully in the eye since its first clinical trials in 1968 in the treatment of various chorioretinal diseases.

During the past few years the argon laser has become an increasingly used modality for the treatment of primary and secondary angle closure glucoma. But, some poorly defined complications remain including the laser's effect on the lens

and intraocular pressure etc.

In this study, the transient change of intraocular pressure followed by argon laser iridotomy was observed in the pigmented and non-pigmented rabbits.

The results were as follow :

1. The number of application of argon laser required for successful iridotomy. The longer the duration of argon laser, the less was the number of application. In the pigmented rabbits, the mean number of application was 194 for long burn technique and 942 for short burn technique.

2. The relationship between the peak intraocular pressure and the laser energy in argon laser iridotomy.

1) The range of peak intraocular pressure followed by argon laser iridotomy was from 8 to 24 mmHg and the range of laser energy was from 12 to 53 Joule.

2) No significant relationship was noted between the laser energy and the intraocular pressure followed by argon laser iridotomy.

3. The change of intraocular pressure followed by argon laser iridotomy.

1) In the pigmented rabbits, the peak intraocular pressure was at 30 minutes after argon laser iridotomy, whereas intraocular pressure was not changed in the non-pigmented rabbits.

2) In the pigmented rabbits, intraocular pressure was higher in the long technique than in the short burn technique.

4. The degree of iritis followed by argon laser iridotomy.

1) In the igmented rabbits, iritis was most prominent at rabbit, postlaser iritis was not found.

2) In the pigmented rabbits, iritis was severer in the long burn technique than in the short burn technique.
Full Text
https://ymlib.yonsei.ac.kr/catalog/search/book-detail/?cid=CAT000000003154
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1. College of Medicine (의과대학) > Others (기타) > 2. Thesis
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/115152
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