옻나무(漆科植物)에 의한 과민성 실험

Abstract

[한글]

[영문]

It has been well know for a long time that Rhus species are belonged botanically to same family called family Anacaracea and their allergenic components are identical because it contains 3-pentadecyl catechol. However, Mason (1954) and some investigators suggest the possibility that some individuals may be sensitive to

component of the oleoresin other than 3-pentadecyl catechol.

By this suggestion, author performed the patch test on 138 individuals with 4 species of Korean Rhus tree (Rhus verniciflua, Rhus trichocarpa, Rhus javanica, and Rhus sylvestris.) and observed the incidence of latent sensitivity to dry leaves of

Rhus trees and urushiol. The patoh test results on sensitivity to Rhus verniciflua, Rhus trichocarpa. Rhus javanice, and Rhus sylvestris showed 35.5%, 27.53%, 21.01%, 28.26%, and 29.71%

respectively and these result could make the suggestion that cross sensitivity between each Rhus trees are few and a certain specific antigenic component may be contained in every Rhus tree leaves.

On animal experiment is concerning, the basic study for the extraction of Rhus tree antigen, author could eaily sensitize the guinea pig with urushiol but couldn't challenge these animal with methanolaceton extract of Rhus leaves.

From these findings, author proposed that Korean Rhus trees are different immunologically to poison ivy tree antigen and a certain specificities of antigenicity contain in each Korean Rhus.

But this postulation will need further experimental study as multiple step fractionation with Rhus tree.