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신생아에서 발생한 Kasabach-Merrit syndrome을 동반한 간혈관종의 약물적 치료와 혈관색전술

Other Titles
 The Treatment of Liver Hemangioma Associated with Kasabach-Merritt Syndrome in Neonates. 
Authors
 신정욱  ;  이철  ;  박국인  ;  박민수  ;  남궁란 
Citation
 Journal of the Korean Society of Neonatology (대한신생아학회지), Vol.12(2) : 179-184, 2005 
Journal Title
 Journal of the Korean Society of Neonatology (대한신생아학회지) 
ISSN
 1226-1513 
Issue Date
2005
MeSH
Liver hemangioma ; Kasabach-Merritt syndrome ; Megadose Methylprednisolone ; α-Interferon ; Interventional embolization
Keywords
Liver hemangioma ; Kasabach-Merritt syndrome ; Megadose Methylprednisolone ; α-Interferon ; Interventional embolization
Abstract
Hemangioma is the most frequent liver tumor in infancy. The treatment of hepatic hemangioma includes medical, surgical, and non-operative interventional therapy. There are no standard medical regimens currently considered consistently effective. MDMP (megadose methylprednisolone) and α-interferon can be used for medical treatment. Interventional occlusion of feeding arteries in symptomatic hepatic hemangioma is considered a safe and effective alternative to early open surgery. Untreated symptomatic patients with heart failure have a high mortality rate. For this reason symptomatic patients with heart failure may require non-operative treatment such as interventional embolization, because hepatic resection is burdened with high risk. We report our experiences of two patients with neonatal liver hemangiomas whose clinical courses were complicated by cardiac failure to whom medical treatment and/or interventional vascular occlusion were done. Both patients had Kasabach-Merritt syndrome complicated with cardiac failure. Initially, the masses were considered unresectable. In one case, we performed interventional therapy in addition to medical treatment. In another case, we tried medical therapy with megadose steroid and α-interferon. Unfortunately, in spite of the treatments, the patients died of severe hemorrhage
Files in This Item:
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DOI
OAK-2005-02264
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Namgung, Ran(남궁란) ORCID logo https://orcid.org/0000-0001-7182-9535
Park, Kook In(박국인) ORCID logo https://orcid.org/0000-0001-8499-9293
Park, Min Soo(박민수) ORCID logo https://orcid.org/0000-0002-4395-9938
Shin, Jung Wook(신정욱)
Lee, Chul(이철)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114986
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