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조기 류마티스관절염의 약물치료

Other Titles
 Paradigm Shifting to Early Treatment of Rheumatoid Arthritis 
Authors
 박민찬  ;  이수곤 
Citation
 JOURNAL OF THE KOREAN MEDICAL ASSOCIATION , Vol.46(11) : 965-971, 2003 
Journal Title
JOURNAL OF THE KOREAN MEDICAL ASSOCIATION(대한의사협회지)
ISSN
 1975-8456 
Issue Date
2003
MeSH
Rheumatoid arthritis ; Early treatment ; Pharmacological management ; Disease modifying antirheumatic drug
Keywords
Rheumatoid arthritis ; Early treatment ; Pharmacological management ; Disease modifying antirheumatic drug
Abstract
The past decade has greatly enhanced our understanding of rheumatoid arthritis (RA). Not only have new drug therapies become available, but this period has witnessed dramatic changes in treatment strategies as well. Since 1989, when the proposal on reversing the pyramid approach (the stepdown bridge concept) was published, the concept of early and aggressive treatment of RA has become the leading paradigm. The theory underlying this approach is based on a better understanding of the devastating long term consequences of RA in most patients, and the logical tenet that irreversible damage must be prevented before it occurs. Evidence has shown the irreversible joint damage in RA occurs early in the disease, making a "wait and see" approach unacceptable. Thus, it appears logical to begin treatment as soon as a diagnosis of RA is confirmed, to slow disease progression by treatment with disease modifying antirheumatic drugs. This review will address the evidence supporting the benefit and the principles of early treatment, as well as the current update on pharmacological management in early RA.
Files in This Item:
T200306826.pdf Download
DOI
10.5124/jkma.2003.46.11.965
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Min Chan(박민찬) ORCID logo https://orcid.org/0000-0003-1189-7637
Lee, Soo Kon(이수곤)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114518
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