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Surgical do's and don'ts of corneal dystrophies

Authors
 Eun Suk Lee  ;  Eung Kweon Kim 
Citation
 CURRENT OPINION IN OPHTHALMOLOGY, Vol.14(4) : 186-191, 2003 
Journal Title
 CURRENT OPINION IN OPHTHALMOLOGY 
ISSN
 1040-8738 
Issue Date
2003
MeSH
Corneal Dystrophies, Hereditary/surgery* ; Humans ; Ophthalmologic Surgical Procedures*
Keywords
corneal dystrophy ; mitomycin C ; phototherapeutic keratectomy ; treatment
Abstract
PURPOSE OF REVIEW: Characteristics of corneal dystrophies have been described with regards to such as location in the cornea, morphology, material composition, and recurrence after penetrating keratoplasty. The main goal of this review is to describe the surgical methods in treating corneal dystrophies. RECENT FINDINGS: Laser in situ keratomileusis (LASIK) has been shown to aggravate corneal deposits in Avellino dystrophy exacerbation LASIK and hence should be avoided. Phototherapeutic keratectomy (PTK) has shown its usefulness in clearing opacities with visual improvement and prevents painful erosion, resulting in delay or postponement of corneal grafting in some corneal dystrophies. Mitomycin-C may be used topically in conjunction with PTK to reduce the recurrence of the opacities. Topical use of antibody to TGF-beta can also be considered to suppress recurrence of corneal opacities after PTK or lamellar keratectomy. SUMMARY: Clinicians must become more adept at choosing a treatment depending on different genotypes and future studies on treatment of corneal dystrophies should be focused on establishing treatment of categorized corneal dystrophies based on their chromosomal mutation.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00055735-200308000-00003&LSLINK=80&D=ovft
DOI
OAK-2003-01198
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114358
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