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정신과 약물의 대사 : 성과 관련된 주제

Other Titles
 Psychotropics Metabolism:Gender-Related Issues 
Authors
 홍현주  ;  김찬형 
Citation
 Korean Journal of Psychopharmacology (대한정신약물학회지), Vol.14(4) : 330-335, 2003 
Journal Title
Korean Journal of Psychopharmacology(대한정신약물학회지)
ISSN
 1017-5717 
Issue Date
2003
MeSH
Gender ; psychotropic metabolism
Keywords
Gender ; psychotropic metabolism
Abstract
There are significant gender differences in pharmacokinetics and pharmacodynamics of psychotropic medications. Gender differences in pharmacokinetics such as drug absorption, bioavailability, drug distribution, drug metabolism, and elimination have clinical implications in terms of plasma levels, drug half-lives, side effects and toxicity. Women and men also show different pharmacodynamic response to a variety of drugs. Additionally female-specific issues such as pregnancy, menopause, oral contraceptive use and menstruation may also have profound effects on drug metabolism. These and other gender-related issues are considered in this article. Gender differences in drug metabolism have the potential to affect appropriate dosing, effectiveness and toxicity. Further research is needed to determine the scope and significance of these sex differences.
Files in This Item:
T200303384.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chan Hyung(김찬형)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113548
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