Cited 72 times in
Focal Hepatic Lesions: Detection and Characterization with Combination Gadolinium- and Superparamagnetic Iron Oxide–enhanced MR Imaging
DC Field | Value | Language |
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dc.contributor.author | 정재준 | - |
dc.contributor.author | 오영택 | - |
dc.contributor.author | 임준석 | - |
dc.contributor.author | 김명진 | - |
dc.contributor.author | 김주희 | - |
dc.contributor.author | 박미숙 | - |
dc.date.accessioned | 2015-07-15T16:38:45Z | - |
dc.date.available | 2015-07-15T16:38:45Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0033-8419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/113313 | - |
dc.description.abstract | PURPOSE: To compare gadolinium- and superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance (MR) imaging for detection and characterization of focal hepatic lesions when different contrast agent administration sequences are used. MATERIALS AND METHODS: Unenhanced, dynamic gadolinium-enhanced, and SPIO-enhanced hepatic MR images were obtained in 134 patients. SPIO-enhanced MR imaging was performed immediately after gadolinium-enhanced dynamic MR imaging in 50 patients, 1 day after gadolinium-enhanced dynamic MR imaging in 40 patients, and before gadolinium-enhanced dynamic MR imaging in 44 patients. Two radiologists independently reviewed the gadolinium image set (unenhanced and gadolinium-enhanced dynamic MR images) and the SPIO image set (unenhanced and SPIO-enhanced MR images) in random order. Lesion detection sensitivity and lesion characterization accuracy were compared by analyzing the area under the receiver operating characteristic curve (Az). RESULTS: Overall lesion detection accuracy for pooled data was significantly higher with the SPIO set (Az = 0.903) than with the gadolinium set (Az = 0.857) (P <.05). When hypovascular lesions were excluded, the detection rate was similar with the two sets. When hepatocellular carcinomas were excluded, the detection rate was significantly higher with the SPIO set (P <.01). Readers were more accurate in differentiating benign from malignant lesions with the gadolinium set (Az = 0.915) than with the SPIO set (Az = 0.847) (P <.01). Detection accuracy tended to be better with the images obtained after the second contrast agent was used. CONCLUSION: Hypovascular lesion detection was better with SPIO-enhanced MR images than with gadolinium-enhanced MR images. Detection and characterization of hypervascular lesions were improved with gadolinium-enhanced MR images. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 719~726 | - |
dc.relation.isPartOf | RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gadolinium* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Image Enhancement/methods* | - |
dc.subject.MESH | Iron* | - |
dc.subject.MESH | Liver Neoplasms/diagnosis* | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Oxides | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Focal Hepatic Lesions: Detection and Characterization with Combination Gadolinium- and Superparamagnetic Iron Oxide–enhanced MR Imaging | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Joo Hee Kim | - |
dc.contributor.googleauthor | Young Taik Oh | - |
dc.contributor.googleauthor | Joon Seok Lim | - |
dc.contributor.googleauthor | Mi Suk Park | - |
dc.contributor.googleauthor | Jae-Joon Chung | - |
dc.identifier.doi | 10.1148/radiol.2283020735 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00951 | - |
dc.contributor.localId | A03712 | - |
dc.contributor.localId | A02390 | - |
dc.contributor.localId | A03408 | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A01463 | - |
dc.relation.journalcode | J02596 | - |
dc.identifier.eissn | 1527-1315 | - |
dc.identifier.pmid | 12881583 | - |
dc.identifier.url | http://pubs.rsna.org/doi/abs/10.1148/radiol.2283020735 | - |
dc.subject.keyword | 12881583 | - |
dc.contributor.alternativeName | Chung, Jae Joon | - |
dc.contributor.alternativeName | Oh, Young Taik | - |
dc.contributor.alternativeName | Lim, Joon Seok | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Kim, Joo Hee | - |
dc.contributor.alternativeName | Park, Mi Sook | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hee | - |
dc.contributor.affiliatedAuthor | Chung, Jae Joon | - |
dc.contributor.affiliatedAuthor | Oh, Young Taik | - |
dc.contributor.affiliatedAuthor | Lim, Joon Seok | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | Park, Mi-Suk | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 228 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 719 | - |
dc.citation.endPage | 726 | - |
dc.identifier.bibliographicCitation | RADIOLOGY, Vol.228(3) : 719-726, 2003 | - |
dc.identifier.rimsid | 55824 | - |
dc.type.rims | ART | - |
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